The total synthesis of acronycine and related compounds from readily available starting materials is described, as are various classes of intermediates useful in the synthesis.
2,6-halo and trifluoromethyl-substituted-benzoic acids, e.g., 2,3,4,6-tetrafluorobenzoic acid or 2-chloro-6-trifluoromethylbenzoic acid, are prepared from substituted 2,4-halo and trifluoromethyl-substituted benzene compounds and are useful as plant growth regulators.
Compounds of the formula ##STR1## wherein R.sub.o, is hydrogen or alkylene-COOR where R is alkyl or hydroxyalkyl, R.sub.1 is hydrogen, alkyl, hydroxyalkyl, alkenyl or acyl, R.sub.2 and R.sub.3 are independently hydrogen, alkyl, alkenyl or alkoxy, R.sub.6 is hydrogen or alkyl, and X is --CH.sub.2 --, --NH--, --S-- or --O--, are suitable as UV absorbers for use in photosensitive organic materials in combination with a sterically hindered amine or hydroxyphenylbenzotriazole derivative.
Compounds of formula (I): ##STR1## wherein R.sub.3, R.sub.4, R.sub.5, R.sub.6, X and Y are defined in the description. Those compounds are used therapeutically in the treatment of cancerous tumours.
A compound of formula ##STR1## wherein R.sub.0, R.sub.1, R.sub.2, R.sub.3, R.sub.6 and X are as defined in claim 1, are suitable for use as UV absorbers for protecting light-sensitive organic materials.
The invention relates to novel 1-(4-R.sub.1 O-phenyl)-2-(4-R.sub.2 -phenyl)-6-R.sub.3 -1,2,3,4-tetrahydroquinolines having antifertility and hypocholesterolemic activities, to their preparation, and to novel intermediates therefor.
