Gelatin capsules filled with an active ingredient or ingredients are protected against solution in the stomach in order that they may reach the intestines and be absorbed therein by providing said capsules with a primary lacquer containing a soluble film-forming colloidal material soluble both in water and in organic solvents and then with a lacquer unaffected by gastric juices and soluble in intestinal juices.
Gastric juice resistant gelatin capsules characterized by a gastric juice resistant outer coating of an anionic polymerizate of methacrylic acid and acrylic acid esters and an intermediate layer between the outer layer and the gelatin shell of a cationic polymerizate of di-lower alkylamino lower alkylmethyl acrylate with other neutral methacrylic esters and a process for preparing the same.
A microgranular preparation having a core of biologically active material that is encapsulated by a water soluble film that is covered by an enteric coating of either an alkali soluble, acid insoluble polymer or a high molecular weight polymer whose structure is substituted with or contains windows of fatty acids or other material capable of being solubilized by intestinal juices. Useful for protecting pH sensitive and other biologically active materials from inactivation or contact with the stomach or rumen, and releasing the same in active form in the intestinal tract, particularly the duodenum.
Apparatus and a method for inhibiting the metabolism of methanol in a human. The apparatus comprises carrier means for a source of ethanol. The carrier means, when combined with a source of ethanol and introduced in the digestive tract of a human being, permits the gradual time release of ethanol from the dietary vaccine into the digestive tract for absorption into the blood stream of an individual. The method comprises introducing the ethanol charged carrier means in the digestive tract of an individual.
A microgranular preparation having a core of biologically active material that is encapsulated by a water soluble film that is covered by an enteric coating of either an alkali soluble, acid insoluble polymer or a high molecular weight polymer whose structure is substituted with or contains windows of fatty acids or other material capable of being solubilized by intestinal juices. Useful for protecting pH sensitive and other biologically active materials from inactivation or contact with the stomach or rumen, and releasing the same in active form in the intestinal tract, particularly the duodenum.
The present invention deals with a pharmaceutical product in unit dosage form and a unit dosage drug delivery system which comprises a multiple layer capsule or housing having two or more layers, the layers being of materials, wherein the outer layer possesses a hydrophilic character and the inner layer possesses a hydrophobic character, and a capsule filling wherein one or more drug substances are admixed, dissolved, suspended or agglomerated in a hydrophobic support.
