The preparation of compounds of the following formulas is disclosed: ##SPC1## In these formulas, R is alkyl, W is hydrogen, alkyl, haloalkyl, phenyl, or phenyl substituted with halo, nitro, or carbomethoxy, X is hydrogen or methyl, Y' is hydrogen or carboxyacyl, Z is hydrogen or alkyl, and n is zero, one, or two. These compounds are used as intermediates to make prostaglandins of the dihydro-PGF.sub.1 -type.
This invention is a group of phenyl-substituted PGE-type, PGF-type, PGA-type and PGB-type compounds, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, labor inducement at term, and wound healing.
