Rodent repellent and rodenticidal compositions containing as the active ingredient 1-(2-imidazolin-2-ylmethyl)-3-ethylindole and methods of combatting rodents comprising orally administering an effective rodent repellent or rodenticidal quantity of the active ingredient. 14 Claims, No Drawings
This invention relates to compounds which are alpha-1 receptor agonists, preferably alpha-1A/L receptor agonists, and which are represented by Formula I: ##STR1## wherein X is --S(O).sub.n -- or --C(O)--, A is C.sub.1-6 alkyl, aryl, heteroaryl, hydroxyalkyl, or --(CH.sub.2).sub.p --NR.sup.a R.sup.b, and the other substituents are as defined in the specification; or individual isomers, racemic or non-racemic mixtures of isomers, or pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing such compounds, methods for their use as therapeutic agents, and methods of preparation thereof.
Disclosed is a porous protein particle for delivering over a period of time an active ingredient impregnated therein, and methods of making and using the same. The protein particles have a median size less than about 50 microns. Active ingredient entrapped in the porous structure is gradually released from the protein particle.
