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[4-(10,11-DIHYDRO-5H-DIBENZO[a,d]CYCLOHEPTEN-10-yL-1-P IPERAZINYL]-ALKYL]-3-ALKYL-2-IMIDAZOLIDINONES AS CNS DEPRESSANTS
   
Document Number
US Patent 3720676
Issued Date
March 13, 1973
Link
Inventors
Schindler; Walter (Riehen/Baseland,CH)
Zuest; Armin (Birsfelden/Baseland,CH)
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Abstract
Compounds of the class of 1-[2- and 3-[4-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-yl)-1-piperazinyl]-alkyl ]-3-alkyl-2-imidazolidinone which can be substituted in 8-position by chloro, methyl or methoxy, and the pharmaceutically acceptable acid addition salts thereof, have a depressant effect on the central nervous system; pharmaceutical compositions comprising these compounds and a method of producing a depressant effect on the central nervous system of warm-blooded animals, are provided; an illustrative embodiment is 1-[2-[ 4-(8-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-yl)-1-piperazinyl] -ethyl]-3-methyl-2-imidazolidinone-bis-maleate.
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Number of Claims:
3
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Owner
Published
March 13, 1973
Application Number
05/061,435
Filed
August 5, 1970
US Classification
544/370   544/381
Int'l Classification
C07D   403/06   (20060101)   C07D   233/32   (20060101)   C07D   233/00   (20060101)   C07D   403/00   (20060101)  
Examiner
Priority Data
Aug 11, 1969 [CH] 12120/69
USPTO Field of Search
260/268TR   260/243A   260/243AN  
Related Patents
4376773 - 10-Substituted 5-cyanomethylene-10,11-dihydro-dibenzo-[a,d]-cycloheptenes, their preparation, and therapeutic agents containing these compounds - Owned by BASF Aktiengesellschaft (DE)

10-Substituted 5-cyanomethylene-10,11-dihydro-dibenzo[a,d]-cycloheptenes, their pharmaceutically tolerated addition salts with acids, processes for their preparation, and their use as drugs, especially as sedatives, hypnotics or tranquilizers.

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Description
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