An implantable dialysis connection assembly for connecting first and second catheters positioned with a vein to first and second terminals of a dialysis machine. The assembly includes a housing having first, second and third recesses extending into a face side thereof. A first port is positioned within the first recess for receiving the first terminal and retaining an end of the first terminal within the first recess. A second port is positioned within the second recess for receiving the second terminal and retaining an end of the second terminal within the second recess. A third port is positioned within the third recess for connecting to a supply of heparin for deposit within the third recess. The third port is connected to the first port for supplying heparin thereto by a first conduit and the third port is connected to the second port for supplying heparin thereto by a second conduit. First and second connection devices connect the first and second ports to the first and second conduits, respectively. In operation, the first terminal causes blood to be removed from the vein through the first catheter and first recess for delivery to and detoxification by the dialysis machine and the second terminal causes detoxified blood to be returned to the vein through the second recess and second catheter, said heparin being supplied to said first and second recesses during dialysis for preventing the blood passing through said first and second recesses from clotting and thereby clogging the first and second terminals.

A cerebrospinal fluid anti-siphoning device for insertion into the human body to provide regulation of fluid being transported from the lateral ventricles to another part of the body. The device includes a fluid housing member through which the cerebrospinal fluid passes. The fluid housing member is adapted to contain a pair of check valves which control fluid flow through the housing member and prevent back flow from a downstream area to an upstream area. A central chamber within the fluid housing member encloses a fluid control mechanism which provides for termination of fluid flow when the downstream pressure becomes too low with respect to the upstream pressure. The fluid control mechanism includes a diaphragm which is displaced from a fluid conduit when flow is passing through the fluid housing member and is positioned contiguous to the conduit opening when the downstream pressure is too low, thereby effectively terminating the flow of the cerebrospinal fluid through the fluid housing member. The device includes a mechanism for manually actuating the flow through the outlet area of the housing member even when the antisiphoning device has been implanted within the human body.

A multiple fluid pulse dispenser comprising a plurality of interconnected fluid reservoirs defined by mating, oppositely directed concavities at least one of which mating concavity is formed from an invertable, preferrably permanently deformable blister. The reservoirs are in fluid communication with an outlet through which the contents of the reservoirs may be dispensed. A preferred embodiment permits fluid to flow through a reservoir after it has been discharged to allow random activation of the individual reservoirs.

An implantable valve for allowing the passage of cerebrospinal fluid (CSF) from a ventricle of the brain to a suitable drainage location in the body includes a movable diaphragm, one side of which is in pressure communication with the drainage location of the body and the other side of which is in pressure communication with the epidural spaces. A valve assembly, actuated by movement of the diaphragm in response to increased epidural pressure controls passage of CSF from the ventricles to the drainage area.

A compensating valve and a drainage system for draining a body fluid from one body region to another body region. The system enables routine drainage at predetermined differential pressures, provides for pumping action, for flushing action to clear the system of obstructive material, and for resisting over-drainage which can occur when the patient makes an abrupt and relatively large change in his position. A compensating valve purpose has a valving action which is proportional to various parameters so as to enable continuous and proportional control for drainage rather than an on/off control.