Amides are prepared by reacting an aromatic amine with an acid chloride in the presence of a neutralizing agent and a catalytic amount of a strongly basic tertiary amine; for example, N-(4-anilinophenyl) methacrylamide prepared by reacting p-aminodiphenylamine with methacryloyl chloride in the presence of sodium carbonate and triethylamine.
In the manufacture of an N-benzyl-N-isopropyl amide by reaction of N-benzyl-N-isopropylamine with an acid chloride, the amide product is obtained in better purity and yield by employing excess benzylisopropylamine as the acid accepting agent and recovering the amine for re-use by reacting the amine hydrochloride by-product with aqueous sodium hydroxide.
The instant invention relates to hydroxyl polyethers which are modified with amide groups and a method of their manufacture. The method includes a first stage wherein a portion of the hydroxyl groups of a polyether polyol are aminated and a second stage wherein the amine groups are reacted with a carboxylic acid, its anhydride, ester or halide. The modified polyesters may be used for the production of polyurethane resins.
An N-substituted amide compound is produced with a high yield by initiating a reaction among a starting amide compound such as a saturated or unsaturated, aliphatic or aromatic carboxylic acid amide, a halogen-substituted compound such as an alkyl halide and a strongly basic substance while maintaining the basic substance in a suspended state.
