Certain 3,4-dihydro-4-oxo and 3-oxo-2H-1,2-benzothiazine-3-carboxamide and 4-carboxamide 1,1-dioxide compounds effective in the treatment of thrombosis are disclosed.
CROSS-REFERENCE TO RELATED APPLICATIONS
The subject application is a continuation-in-part of co-pending application Ser. No. 114,037, filed Feb. 9, 1971, now abandoned said application Ser. No. 114,037 in turn being a continuation of application Ser. No. 829,713, filed June 2, 1969, and now abandoned.
The invention relates to novel tropone derivatives, of antiinflammatory, analgesic and antirheumatic activity, of the formula: ##STR1## wherein R.sup.1 is hydrogen or lower alkyl, R.sup.2 is hydrogen, hydroxy, halogen, lower alkyl, or lower alkoxy, and R.sup.3 is hydrogen or acyl, and pharmaceutically acceptable salts thereof.
The present invention relates to novel enolamide type compounds, pharmaceutical compositions, and methods of use thereof, useful in the treatment of diseases in which products of lipoxygenase enzyme activity or the action of leukotrienes contribute to the pathological condition.
