Brominated sulfoacetic acid amides of the formula R.sub.1 R.sub.2 NCOCBr.sub.x H.sub.2.sub.-x SO.sub.2 NR.sub.1 R.sub.2 in which R.sub.1 and R.sub.2 are independently selected from hydrogen and lower alkyl or, in conjunction with the nitrogen atom, from a heterocycle which may contain an oxygen hetero atom and x is an integer from 1 to 2. The compounds are prepared by brominating amides of sulfoacetic acid. The compounds have antimicrobial activity.
Alkane sulfonamides with an electron withdrawing function .beta. to the sulfonamide group are topically effective carbonic anhydrase inhibitors useful in the treatment of elevated intraocular pressure and glaucoma.
