Mammals are anesthetized by administration of 2-arylalkyloxy benzamides. When administered, the 2-arylalkyloxy benzamides of this invention are useful for the production of anesthesia, such as local anesthesia, in mammals. When administered intramuscularly, compounds of this invention show significant anesthesia when compared with xylocaine. Again, intradermic injections of 0.2 ml. of a solution of such a compound in concentrations varying from 0.1 to 1.25 mg./ml. effect suppression of platysma tremor produced by the prick of a pin in guinea pigs. The LD.sub.50 dosage of the compounds evaluated on mice and rats proved compatible in therapeutic use on mammals.
This application is a division of U.S. Pat. application Ser. No. 324,509, filed Jan. 17, 1973. The application Ser. No. 324,509 is a division of U.S. Pat. application Ser. No. 108,963, filed Jan. 22, 1971, now U.S. Pat. No. 3,723,416, which is a continuation-in-part of U.S. Pat. application Ser. No. 714,795, filed Mar. 21, 1968, now U.S. Pat. No. 3,594,417.
Priority Data
Apr 03, 1967 [FR] 67.101328 Jun 23, 1967 [FR] 67.111808
