3-(.gamma.-aminopropyl)-piperidines can be manufactured by hydrogenating certain bis-cyanoethylated aldimines in the presence of a catalyst and preferably in the presence of an organic solvent. The hydrogenation can be executed at temperatures up to 200.degree.C either without application of pressure or under pressure. Cyclisation occurs with a primary amin being split off. The piperidine derivatives, obtainable according to this invention are suitable as curing agents for epoxy resins.
This application is a continuation-in-part-application of our copending application Ser. No. 325,462, filed Jan. 22, 1973, which in turn is a continuation application of our copending application Ser. No. 133,445, filed Apr. 12, 1971, now abandoned.
The invention is related to compounds, being useful in treating psychosis, of the formula: ##STR1## wherein R.sup.1 is lower-alkyl, or phenyl-lower-alkyl; R.sup.2, R.sup.3 and R.sup.4 are the same or different lower-alkyl; n is zero or one; R.sup.5 is hydrogen, lower-alkyl, C.sub.3 -C.sub.7 -monocyclic cycloalkyl, lower-alkoxy, phenyl, phenyl-lower-alkyl, phenyl-lower-alkyl in which the phenyl ring is substituted in the 2, 3, or 4-position by one to two, the same or different, halogen substituents, or R.sup.5 is a 5-membered aromatic monocyclic heterocycle selected from the group consisting of thienyl, furanyl and isoxazolyl; R.sup.6 is hydrogen or lower-alkyl; or when n is zero, R.sup.5 and R.sup.6 together are --(CH.sub.2).sub.m -- wherein m is an integer from four to six; with the proviso that when R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are methyl, n is zero and R.sup.6 is hydrogen or methyl, R.sup.5 cannot be hydrogen; further provided that when n is zero, R.sup.5 cannot be lower-alkoxy, phenyl, or a 5-membered aromatic monocyclic heterocycle, or a pharmaceutically acceptable acid-addition salt thereof.
Acidic gases containing carbon dioxide are removed from a normally gaseous mixture by absorbing CO.sub.2 from the gaseous mixture with an aqueous solution comprising a basic alkali metal salt or hydroxide and an activator or promoter system for the salt or hydroxide which contains (i) at least one non-sterically hindered diamine defined as having both a primary and a tertiary amino moiety wherein the primary amino moiety is attached to a primary carbon atom, and (ii) an amino acid, and desorbing at least partially the absorbed CO.sub.2 from the aqueous solution.