There is provided a pharmaceutical composition in dosage unit form comprising (a) 1 - 100 mg. of glycyrrhetinic acid and/or of at least one anti-inflammatory active derivative thereof, in admixture with (b) 1 - 50% by weight of alginic acid and/or at least one non-toxic salt thereof and/or of at least one carboxyalkyl-cellulose and/or of at least one non-toxic salt thereof, (c) 1 - 30% by weight of at least one non-toxic carbonate and/or bicarbonate and (d) 0 - 30% by weight of at least one antacid compound.
This application generally relates to subject matter which is similar to that disclosed in applicants' copending application Ser. No. 419,486, filed Nov. 28, 1973.
The present invention provides a water-soluble or water-dispersible particulate pharmaceutical composition comprising, per one part by weight of glycyrrhetinic acid and/or glycyrrhetinic acid derivative (as hereinbefore defined), 10 to 100 parts by weight of lactose and/or sorbitol, 10 to 50 parts by weight of at least one buffer selected from sodium citrate, potassium citrate, sodium tartrate, potassium tartrate, sodium malate and potassium malate and 0.1 to 10 parts by weight of disodium edetate.
Methods and compositions for treating infectious diseases comprising introducing such compositions, which consist essentially of one or more glycyrrhizie triterpenoid compounds, such as, for example, carbenoxolone, glycyrrhizin or cicloxolone, are disclosed. Therapy by inhalation is contemplated.
The present invention provides a pharmaceutical composition in the form of a water-containing cream which contains at least one glycyrrhetinic acid derivative (as hereinbefore defined), together with at least one non-toxic, water-soluble salt of zinc, calcium and/or magnesium as stabilizer.
The invention is concerned with new chemical compounds being the hemiesters of steryl glycosides, methods of preparing these hemiesters, and pharmaceutically, particularly anti-inflammatory, compositions containing the new hemiesters.
