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Anti-hypertensive polycyclic compounds for treating hypertension
   
Document Number
US Patent 3973023
Issued Date
August 3, 1976
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Abstract
Chromanols of the formula (II) ##SPC1## wherein R.sub.1 is a non-aromatic hydrocarbon group of 1-20 carbon atoms, R.sub.2 is a hydrocarbon group of 1-20 carbon atoms optionally substituted by a halogen atom and X is an optionally salted, etherified or acylated hydroxyl group, and N-oxides, acid-addition and quaternary salts thereof are shown to have anti-hypertensive activity. Their preparation and compositions containing them are described.
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Anti-hypertensive polycyclic compounds for treating hypertension - US Patent 3973023 Drawing
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Number of Claims:
14
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Published
August 3, 1976
Application Number
05/517,001
Filed
October 22, 1974
US Classification
514/337  
Int'l Classification
A61K   31/44   (20060101)   C07G   11/00   (20060101)  
Examiner
Assistant Examiner
Parent Case
This is a division of application Ser. No. 324,222 filed Jan. 10, 1973, now U.S. Pat. No. 3,853,899 issued Dec. 10, 1974.
Priority Data
Jan 26, 1972 [UK] 3654/72
USPTO Field of Search
424/263  
Related Patents
5143924 - Oxodihydropyridyl chroman derivatives - Owned by Merck Patent Gesellschaft mit beschrankter Haftung (Darmstadt,DE)

Novel chroman derivatives of the formula I ##STR1## in which R.sup.1 to R.sup.6 and Z have the meanings given in Patent Claim 1, and their salts show effects on the cardiovascular system and can be used for the treatment or prophylaxis of cardiac insufficiency, angina pectoris, high blood pressure, incontinence and alopecia.

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Description
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