3-(5,7-Dimethyl-2-hydroxy-4-oxo-6,8-decadienyl)-glutarimide is prepared by cultivating Streptomyces pluricolorescens var. yamashitaensis (S-885) ATCC No. 21956 in an aqueous nutrient broth containing a carbohydrate and a source of organic nitrogen until said broth achieves substantial antiviral activity, and recovering said antibiotic from said culture broth. This antibiotic is effective against the viruses of polio and A-type influenza.
This is a division of application Ser. No. 525,222, filed Nov. 19, 1974, now U.S. Pat. No. 3,926,131 which is a division of application Ser. No. 391,996, filed Aug. 27, 1973 now U.S. Pat. No. 3,880.858.
