Various derivatives of barbituric acid and of diphenylhydantoin are described in which alkoxymethyl or benzyloxymethyl groups are attached to the nitrogen atoms of the rings. Therapeutic compositions containing these compounds and their use as anticonvulsant agents are described.
This application is a division of copending application Ser. No. 888,943, filed Dec. 29, 1969, now pending which in turn is a continuation in part of application Ser. No. 749,972, filed Aug. 5, 1968, now abandoned.
There are disclosed novel oxopyrimidine derivatives of the general formula ##STR1## wherein R.sub.1 and R.sub.2 may be the same or different and are each hydrogen or lower alkyl optionally substituted by lower alkoxy, and R.sub.3 and R.sub.4 may be the same or different and are each phenyl optionally substituted by lower alkyl or halogen, provided that when R.sub.1 and R.sub.2 are both hydrogen, R.sub.3 and R.sub.4 are each substituted phenyl. Pharmaceutical compositions containing these compounds and their use as anticonvulsant, antianxiety and muscle relaxant agents are described.
A carbon black reactor capable of producing carbon black of varying properties is disclosed comprising a longitudinally extending reactor tunnel having combustion, reaction, and quench zones in contiguous axial alignment. First and second venturi flow constrictions are provided in spaced relationship in the reaction zone of the reactor tunnel to create a pressure profile in the reaction zone. The pressure profile produces carbon blacks having certain physical properties. The second venturi constriction may be provided with means for varying the effective area of the second constriction for altering the pressure profile in the reactor tunnel to vary the properties of the produced carbon black. Further, carbon blacks of varying properties are produced for a given pressure profile by varying the point and direction of feedstock oil injection into the reaction zone.
This invention relates to novel photooxidation products, and derivatives thereof, of Merocyanine 540, their preparation and their uses as anticancer and antiviral agents.
Disclosed herein are buffers and methodologies for the capillary zone electrophoretic analysis of hemoglobin and the variants of hemoglobin. In a particularly preferred embodiment, the buffer comprises at least about 100 mM of barbituric acid, derivatives of barbituric acid, combinations of barbituric acid and derivatives of barbituric acid, and combinations of the derivatives of barbituric acid, and has a pH of at least about 8.0.
