In the preparation of (poly)cyclic polyethers by a cyclic Williamson synthesis, the improvement of contacting the reactants in a hindered (C.sub.4 -C.sub.14) alkanol. For example, bis-chloroethyl ether and the disodium salt of tetraethylene glycol are contacted in t-butanol to produce the cyclic polyether ##STR1## in high yields.
Novel compounds of the formula ##STR1## wherein --D-- is a methylene group which is a member of an oxetane or a 1,3-dioxane ring, --R-- is ethylene or propylene bearing from 0-6 methyl groups and m and n are lower integers. For example, a compound of the formula ##STR2## is contacted with dilute HCl to give a monomer ##STR3## which is copolymerized with a diisocyanate to give a copolymer which removes SO.sub.2 from gas streams.
A process is described for the preparation of substituted oxyacetaldehydes and cyclic acetals thereof according to the reaction sequence: ##STR1## wherein R.sub.1 and R.sub.2, taken together form a lower alkylene group; wherein R.sub.3 is alkyl, alkenyl or alkadienyl and X is halogen selected from the group consisting of chlorine and bromine, the reaction (i) being carried out (1) using a "phase transfer agent" and (2) in a two phase system.
A composition for removing or inactivating harmful components including virus from blood or other extracellular liquids comprises a crownether compound substituted on a polysaccharide, preferably dextrane. The composition may be soluble in water, preferably for intraveneous application, or insoluble for extracorporeal application.
A composition for removing or inactivating harmful components including virus from blood or other extracellular liquids comprises a crown ether compound substituted on a polysaccharide, preferably dextran. The composition may be soluble in water, preferably for intraveneous application, or insoluble for extracorporeal application.
