Hydroxyalkyl and aryl or heterocyclic substituted-4,5-dihydropyridazin(2H)-3-ones and diazabicyclo-ene-ones e.g., 6-(p-chlorophenyl)-2-(2-hydroxybutyl)-4,5-dihydropyridazin(2H)-3-one are prepared by condensing 1-hydrazino-2-alkanols with aryl or heterocyclic-.gamma.-keto acids and are useful as central nervous system depressants.
This is a division of application, Ser. No. 614,539 filed Sept. 18, 1975, which issued as U.S. Pat. No. 4,055,644 on Oct. 25, 1977, which in turn is a division of application Ser. No. 409,653 filed Oct. 25, 1973, which issued as U.S. Pat. No. 3,931,176 on Jan. 6, 1976, which in turn is a continuation-in-part of copending U.S. patent application Ser. No. 366,670, filed June 4, 1973, now abandoned, which in turn is a continuation-in-part of copending U.S. patent application Ser. No. 182,159, filed Sept. 20, 1971, now abandoned, which in turn is a continuation-in-part of U.S. patent application Ser. No. 166,565, filed July 27, 1971, now abandoned, which in turn is a continuation-in-part of copending U.S. patent application Ser. No. 88,976, filed Nov. 12, 1970, now abandoned.
