A method for treating pathological conditions of the nail, particularly onychomycosis, is described. The method comprises the breaching the protective keratin of the nail to form an opening therein, placing a caustic-keratolytic agent in the opening to enlarge it, and treating the nail through the opening with topical therapeutic agents for the pathological condition being treated, for instance, an antifungal agent for onychomycosis. In addition, thick callouses and painful plantar warts can be removed with modifications of this method.
A novel treatment for wart and related disorders such as papillomas derived from extracts of pepper, ginger, and related plant species containing vanillyl (FIG. 3), and piperidine (FIG. 7) ring structures typical of the pungent principals found in pepper, and ginger. The pepper extracts, which also possess antifungal properties are demonstrated in the topical treatment of warts.
The invention relates to a nail lacquer for treating onychomycosis, comprised of a film-forming agent, an antimycotically active substance, and urea, wherewith the antimycotically active substance and the urea are liberated from the lacquer when the lacquer is applied. A preferred formulation comprises cellulose derivative(s) as film former(s), clotrimazole as the antimycotic (present in the amount of 5-30 wt. % based on the weight of the non-volatile components), urea (present in the amount of 15-60 wt. % based on the weight of the non-volatile components), and dibutyl phthalate as a plasticizer, in a solvent mixture comprised of acetone and ethanol.
Position locating device for interstitial radiotherapy of a body portion comprising a flexible sheet member for being received about and conformed with a body portion which is to receive radiotherapy, the sheet member having a plurality of spaced position locating means, and attachment means for releaseably securing the sheet member about the body portion. The position locating means of the sheet member comprises a plurality of spaced openings arranged in rows and columns, and the attachment means comprises a pair of clamping units securing a plurality of bands with the ends of the sheet member. The clamping units are detachably secured with the sheet member for being replaced and repositioned therewith and the first ends of the bands are pivotally secured with the respective clamping units, while the second ends of each of the bands of one of the clamping units is detachably securable with a corresponding one of the second ends of the bands of the other clamping unit. The method comprises positioning a flexible sheet member having a plurality of spaced openings over a body portion which is to receive interstitial radiotherapy, conforming the sheet member with the surface of the body portion and securing its position thereon, marking the locations of selected openings of the sheet member onto the surface of the body portion, and thereafter removing the sheet member from the body portion.
An artificial nail includes an acrylic top layer mounted on a collagen support layer in the form of a mesh. The proximal end of the nail includes a plurality of anchor points, preferably three semi-circular anchor points. The proper size nail is selected by use of sizers. The toe or finger is prepared for implantation of the artificial nail by a puncturing tool which has a pattern of tines on its flat base.
Onychomycosis is a fungal infection of the nail bed and is difficult to treat topically because penetration of the nail plate is difficult, and systemic antifungal treatments are prone to side effects and drug interactions.The present invention treats onychomycosis by applying an antifungal composition to the nail bed directly using a solid, semi-solid, or flowable carrier. The carrier can be in the form of a semi-solid into which the user digs and scrapes the nail, a solid carrier can be inserted directly under the nail in contact with the nail bed, or a flowable composition can be injected in contact with the nail bed.
