There are disclosed novel 3-amino(and substituted amino)-hydroxy (and dihydroxy)-1,2,3,4-tetrahydrocarbazoles having positive inotropic activity and methods and compositions for the use thereof in treating the failing heart in mammals afflicted with congestive heart failure.
This application is a continuation-in-part of copending application Ser. No. 465,238, filed Apr. 29, 1974, now abandoned, in turn a continuation-in-part of application Ser. No. 425,205, filed Dec. 17, 1973, now U.S. Pat. No. 3,959,309, issued May 25, 1976 (of which pending application Ser. No. 579,157, filed May 20, 1975, now U.S. Pat. No. 4,062,864, also is a continuation-in-part), in turn a continuation-in-part of application Ser. No. 172,206, filed Aug. 16, 1971, now abandoned, in turn a continuation-in-part of application Ser. No. 793,545, filed Jan. 23, 1969, now abandoned, in turn a continuation-in-part of application Ser. No. 659,606, filed Aug. 10, 1967, now U.S. Pat. No. 3,642,816, issued Feb. 15, 1972.
USPTO Field of Search
260/315
424/274
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