The invention comprises a 5,5-diphenyl-2,4-imidazolidinedione-guaran complex formed by reacting an aqueous solution of guaran with an organic solvent solution of 5,5-diphenyl-2,4-imidazolidinedione. The invention also includes a therapeutic composition and method wherein the active agent is the guaran 5,5-diphenyl-2,4-imidazolidinedione complex.
A controlled release powder containing discrete micro-particles for use in edible, pharmaceutical and other controlled release compositions is disclosed. The micro-particles have an average size in the range of from 0.1 to 125 .mu.m. Each of the micro-particles is in the form of a micromatrix of an active ingredient uniformly distributed in at least one non-toxic polymer. The micro-particles have a predetermined release of active ingredient when the dissolution rate thereof is measured according to the Paddle Method of U.S. Pharmacopoeia XX at 37.degree. C. and 75 r.p.m.
