|
|
|
| United States Patent | 4587976 |
| Link to this page | http://www.wikipatents.com/4587976.html |
| Inventor(s) | Schmid; Johann J. (Buchs, CH);
Thie; Werner (Dielsdorf, CH) |
| Abstract | When measuring signals are detected from a living being by means of
electrodes, the moments of time associated with the starting point and the
end point of the measuring signal are not unambiguously defined. In order
to determine the starting point and the end point, a predetermined period
of time of a selected signal pattern is subdivided into a first time
interval and into a second time interval. The minimum distance between
measuring points within the first time interval, on the one hand, and
measuring points within the second time interval, on the other hand, is
determined. The moments of time at which the measuring point of the first
time interval associated with the minimum distance and the measuring point
of the second time interval associated with the minimum distance are
detected, are considered to constitute the starting point and the end
point, respectively. |
|
|
|
Title Information  |
|
|
|
|
|
Drawing from US Patent 4587976 |
|
|
Method of, and apparatus for, determining the starting point and the end
point of closed signal patterns |
|
|
|
|
|
| Publication Date |
May 13, 1986 |
|
|
|
|
|
| Filing Date |
January 22, 1985 |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Priority Data |
Jan 25, 1984[CH]327/84 |
|
|
|
|
|
|
|
|
|
|
|
Title Information  |
|
|
References  |
|
|
| *references marked with an asterisk below are user-added references |
|
U.S. References |
|
|
|
|
|
|
U.S. References |
|
|
Foreign References |
|
|
|
|
|
|
Foreign References |
|
|
Other References |
|
|
|
|
|
|
Other References |
|
|
|
|
|
References  |
|
|
|
|
|
| Market Size |
|
Estimate the gross annual revenues of the relevant market
sector:
|
| | |
| |
|
|
| Market Share |
|
Estimate the percentage of the relevant market sector this invention will capture:
|
| | |
| |
|
|
| Reasonable Royalty |
|
What percentage of gross sales should the inventor or assignee be paid?
|
| | |
| |
|
|
|
Public's "Guesstimation" of Royalty Value
|
| Market Size | N/A | [No votes] | | x | Market Share | N/A | [No votes] | | x | Reasonable Royalty | N/A | [No votes] |
| | N/A | |
| |
|
|
|
|
|
|
|
|
|
|
|
|
Market Review  |
|
|
Technical Review  |
|
|
Claims  |
|
|
What we claim is:
1. A method of determining the starting point and the end point of a
spatial closed signal pattern in a time sequence of individual ones of
such spatial closed signal patterns, each of which is constituted by a
series of measured signals, said method comprising the steps of:
arrangiang a predetermined number of electrodes in a predetermined
configuration at a living being to be investigated and receiving said time
sequence of spatial closed signal patterns by means of said electrodes;
subdividing a predetermined period of time which is associated with a
selected one of said individual spatial closed signal patterns, into a
first time interval and a second time interval;
sampling said selected individual spatial closed signal pattern and
determining, at each one of a predetermined number of sampling moments
associated with said first time period, the distance between a
predetermined number of sampling points associated with said predetermined
number of sampling moments in said first time interval, on the one hand,
and a predetermined number of sampling points associated with a
predetermined number of sampling moments in said second time interval, on
the other hand;
ascertaining the minimum value of said distances determined between said
predetermined sampling points associated with said first time interval and
said predetermined sampling points associated with said second time
interval; and
defining a selected sampling point associated with said first time interval
and a selected sampling point associated with said second time interval,
between which said minimum distance exists, as said starting point and as
said end point, respectively, of said selected individual spatial closed
siqnal pattern.
2. The method as defined in claim 1, further including the step of:
selecting a reference point by means of which said first time interval and
said second time interval are separated from each other.
3. The method as defined in claim 1, wherein:
the step of subdividing said predetermined period of time which is
associated with said selected individual spatial closed signal pattern
into said first time interval and said second time interval, entails the
step of fixing said first time interval and said second time interval by
means of a common moment of time at which a spatial slope of said selected
individual spatial closed signal pattern has a predetermined value.
4. The method as defined in claim 3, further including the step of:
presetting a predetermined spatial slope value for said spatial slope of
said selected individual spatial closed signal pattern at said common
moment of time;
determining said common moment of time which fixes said first time interval
and said second time interval, in a first approximation, by the moment of
time at which the spatial slope of a first one of said time sequence of
individual spatial closed signal patterns has a spatial slope value
essentially equal to said preset predetermined spatial slope value;
determining individual spatial slope values of further individual spatial
closed signal patterns following said first individual spatial closed
signal pattern in said time sequence; and
determining an average spatial slope value from said individual spatial
slope values determined for said further individual spatial closed signal
patterns and using such average value for presetting said predetermined
spatial slope value for each one of said individual spatial closed signal
patterns at said common moment of time.
5. The method as defined in claim 1, further including the steps of:
projecting each one of said individual spatial closed signal patterns into
an orthogonal coordinate system; and
determining spatial distances in said orthogonal coordinate system into
which each said individual spatial closed signal pattern has been
projected.
6. A method of recording a measured signal constituted by measured data
which vary in time and space and form a time sequence of recurring
individual spatial closed signal patterns, said method comprising the
steps of:
receiving and recording as a function of time the measured data which
constitute said measuring signal;
selecting a reference point for each one of said recurring individual
spatial closed signal patterns;
determining, on the basis of said selected reference point, for each one of
said recurring individual spatial closed signal patterns, a first time
interval and a second time interval located at opposite sides of said
reference point;
sampling a preselectable number of first measured data and related first
moments of time which are associated with said first time interval and
sampling a preselectable number of second measured data and related second
moments of time which are associated with said second time interval;
determining the spatial distance between the measured data associated with
said sampled first measured data and the measured data associated with
said sampled second measured data; and
determining a pair of sampled first and second measured data with which a
minimum value of said spatial distance is associated and thereby
ascertaining a starting point and an end point for each one of said
recurring individual spatial closed signal patterns.
7. The method as defined in claim 6, further including the steps of:
placing a predetermined number of sensors in a predetermined spatial
configuration at an object to be investigated; and
the step of receiving and recording said measured data as a function of
time entailing the step of receiving and recording the variation in time
and space of a predetermined characteristic of said object by means of
receiving and storing measured data which are measured by said sensors and
which vary in time and space in correspondence with said predetermined
characteristic of said object to be investigated.
8. The method as defined in claim 7, wherein:
said step of selecting said reference point includes the step of selecting,
in a selected one of said recurring individual spatial closed signal
patterns, a point at which said selected individual spatial closed signal
pattern has a predetermined spatial slope.
9. The method as defined in claim 8, wherein:
said step of selecting said reference point includes the step of selecting
as said reference point a point at which said selected individual closed
signal pattern has a maximum spatial slope.
10. The method as defined in claim 9, wherein:
said step of selecting said point at which said selected individual spatial
closed signal pattern has a maximum spatial slope, includes the step of
selecting a predetermined time interval substantially encompassing said
selected individual spatial closed signal pattern and subdividing said
time interval into a sequence of successive sections, determining the
spatial slope in each one of said successive sections and selecting the
section having a maximum spatial slope; and
defining the first occurring moment of time associated with said section
having the maximum slope as said point constituting said reference point.
11. The method as defined in claim 10, further including the steps of:
repeating the determination of the maximum spatial slope of said individual
spatial closed signal pattern for different ones of said sequence of said
individual spatial closed signal patterns; and
determining an average value of the maximum spatial slope of the individual
spatial closed signal patterns from the maximum spatial slopes determined
for said different individual spatial closed signal patterns and for the
selected individual spatial closed signal patterns.
12. The method as defined in claim 11, further including the step of:
defining a predetermined upper value and a predetermined lower value of
said maximum spatial slope and thus a predetermined spread of acceptable
values for said maximum spatial slope of said individual spatial closed
signal patterns at said reference point.
13. The method as defined in claim 7, wherein:
said step of determining said first time interval includes the step of
selecting as said first time interval a time interval which extends from
the moment of time associated with said reference point to a preceding
moment of time in the region of the starting point of said selected
individual spatial closed signal pattern; and
said step of determining said second time interval including the step of
selecting as said second time interval a time interval extending from said
moment of time associated with said reference point to a following moment
of time in the region of the end point of said selected individual spatial
closed signal pattern.
14. The method as defined in claim 7, wherein:
said step of placing a predetermined number of sensors in a predetermined
spatial configuration at an object to be investigated includes the step of
placing a predetermined number of electrodes in said predetermined spatial
configuration at the body of a living being; and
the step of receiving and recording said measured data including the step
of measuring and recording the variation in time and space of an electric
potential which occurs in said living being, in the form of a vector
diagram constituted by a time sequence of recurring individual spatial
closed electrode potential patterns which are constituted by a
predetermined number of loops and which are received and recorded in a
rectangular coordinate system defined by said predetermined spatial
configuration of said predetermined number of electrodes.
15. The method as defined in claim 14, further including the steps of:
scanning said predetermined number of electrodes at a predetermined
scanning frequency; and
feeding said measured electrode potentials measured at related scanning
moments of time via an analog-to-digital converter to a measured data
storage and storing therein said measured individual spatial closed
electrode potential patterns in digital form at associated addresses which
correspond to the related scanning moments of time.
16. The method as defined in claim 15, further including the steps of:
operatively connecting said measured data storage to an arithemetic logic
unit;
transmitting successively measured electrode potentials mesured at related
scanning moments of time within a predetermined time interval
substantially including a preselected loop of a selected individual
spatial closed electrode potential pattern from said measured data storage
to said arithemetic logic unit and determined by means of two of said
successively measured electrode potentials and two of said related
scanning moments of time a predetermined slope of said preselected loop in
said rectangular coordinate system;
determining a predetermined spatial slope of said preselected loop of said
selected individual spatial closed electrode potential pattern from the
predetermined slopes in said rectangular coordinate system;
defining as said reference point the first occurring scanning moment of
time associated with said predetermined spatial slope; and
transmitting said predetermined spatial slope of said preselected loop of
said selected individual spatial closed electrode potential pattern to
said measured data storage.
17. The method as defined in claim 16, wherein:
said step of determining said predetermined slope of said preselected loop
in said rectangular coordinate system entails the step of determining by
means of two successively measured electrode potentials and two of said
related scanning moments of time a maximum variation in the electrode
potential with time and thus a maximum slope;
said step of determining the predetermined spatial slope of said
preselected loop entails the step of determining the maximum spatial
slope; and
said step of transmitting said predetermined spatial slope entails the step
of transmitting said maximum spatial slope of said preselected loop to
said measured data storage.
18. The method as defined in claim 17, wherein:
said steps of determining and transmitting said maximum spatial slope of
said preselected loop of said selected individual spatial closed electrode
potential pattern includes the step of determining and transmitting the
maximum positive spatial slope.
19. The method as defined in claim 18, wherein:
said step of placing a predetermined number of electrodes and measuring and
recording the variation in time and space of the electrode potential
includes the step of picking up a time sequence of recurring vector
cardiograms containing a predetermined number of loops and constituting
said sequence of recurring individual spatial closed electrode potential
patterns;
said step of transmitting successive measured electrode potentials measured
at related scanning moments of time within a predetermined time interval
includes the step of selecting a time interval of a duration approximately
equal to the duration of a QRS-loop of an individual one of said recurring
vector cardiograms; and
said step of defining said reference point includes the step of determining
the first occurring scanning moment of time which is associated with said
maximum positive slope in the QRS-loop of said individual vector
cardiogram.
20. The method as defined in claim 19, further including the steps of:
determining the maximum positive spatial slopes of the preselected loops of
a predetermined number of individual ones of said time sequence of
recurring vector cardiograms;
determining an average maximum positive spatial slope from the maximum
positive spatial slopes determined for each one of the preselected loops
of said predetermined number of individual vector cardiograms;
comparing the average maximum positive spatial slope with the individual
maximum positive spatial slopes of the preselected loops of said
predetermined number of individual vector cardiograms, and, as a result of
such comparison, determining upper and lower limiting values and a
predetermined acceptable spread of maximum positive spatial slope values;
and
transferring said upper and lower limiting values of said spread of
acceptable maximum positive spatial slope values to said measured data
storage.
21. The method as defined in claim 20, further including the steps of:
selecting from said predetermined number of individual vector cardiograms a
selected number of individual vector cardiograms, the preselected loops of
which have a maximum positive spatial slope value within said
predetermined acceptable spread of maximum positive spatial slope values;
determining the first one in the time sequence of said selected number of
individual vector cardiograms;
transferring a first sample of electrode potentials measured during a first
time interval, which extends from a preselected moment of time preceding
said reference point of said preselected loop of the first one of said
selected number of individual vector cardiograms to a first moment of time
preceding said preselected moment of time, from said measured data storage
to a first data storage operatively connected thereto by means of said
data and address bus;
supplying addresses associated with said first sample of measured electrode
potentials from said measured data storage to a first address counter by
means of said data and address bus;
transferring a second sample of electrode potentials measured during a
second time interval, which extends from a further preselected moment of
time following said reference point of said preselected loop of said first
one of said selected number of individual vector cardiograms to a second
moment of time following said further preselected moment of time, from
said measured data storage to a second data storage by means of said data
and address bus; and
supplying addresses associated with said second sample of measured
electrode potentials from said measured data storage to a second address
counter by means of said data and address bus.
22. The method as defined in claim 21, further including the step of:
selecting as said first time interval a time interval extending from a
preselected moment of time preceding said reference point by about 20
milliseconds to a first moment of time preceding said reference point by a
time period in the range of 60 to 140 milliseconds and including the
starting point of said preselected loop of said first one of said selected
number of individual vector cardiograms; and
selecting as said second time interval a time interval extending from a
further preselected moment of time following said reference point by about
20 milliseconds to a second moment of time following said reference point
by a time period in the range of 160 to 200 milliseconds and including the
end point of said preselected loop of said first one of the selected
number of individual vector cardiograms.
23. The method as defined in claim 18, further including the steps of:
controlling the determination of said spatial slope of said preselected
loop of said selected individual spatial closed electrode potential
pattern by means of a program sequencer operatively connected to said
arithmetic logic unit and to said measured data storage by means of a data
and address bus.
24. The method as defined in claim 16, further including the steps of:
determining the spatial slopes of the preselected loops of a predetermined
number of individual spatial closed electrode potential patterns of said
time sequence of individual spatial closed electrode potential patterns;
determining an average spatial slope from the spatial slopes determined for
each one of the preselected loops of the predetermined number of said
individual spatial closed electrode potential patterns;
comparing the average spatial slope with the individual spatial slopes of
the preselected loops of said predetermined number of individual spatial
closed electrode potential patterns, and, as a result of such comparison,
determining upper and lower limiting values and a predetermined acceptable
spread of spatial slope values; and
transferring said upper and lower limiting values of said spread of
acceptable spatial slope values to said measured data storage.
25. The method as defined in claim 24, further including the steps of:
selecting from said predetermined number of individual spatial closed
electrode potential patterns a selected number of individual spatial
closed electrode potential patterns, the preselected loops of which have a
spatial slope value within said predetermined acceptable spread of spatial
slope values;
determining the first one in the time sequence of said selected number of
individual spatial closed electrode potential patterns;
transferring a first sample of electrode potentials measured during a first
time interval, which extends from the moment of time associated with said
reference point of said preselected loop of said first one of said
selected number of individual spatial closed electrode potential patterns
to a preceding moment of time in the region of the starting point of said
preselected loop of said first one of said selected number of individual
spatial closed electrode potential patterns, from said measured data
storage to a first data storage operatively connected thereto by means of
said data and address bus;
supplying addresses associated with said first sample of measured electrode
potentials from said measured data storage to a first address counter by
means of said data and address bus;
transferring a second sample of electrode potentials measured during a
second time interval, which extends from said moment of time associated
with said reference point of said preselected loop of said first one of
said selected number of individual spatial closed electrode potential
patterns to a following moment of time in the region of the end point of
said preselected loop of said first one of the selected number of
individual spatial closed electrode potential patterns, from said measured
data storage to a second data storage by means of said data and address
bus; and
supplying addresses associated with said second sample of measured
electrode potentials from said measured data storage to a second address
counter by means of said data and address bus.
26. The method as defined in claim 25, further including the steps of:
storing the measured electrode potential associated with said reference
point and the address of said reference point at a null address in said
measured data storage;
determining the spatial distances between the first measured electrode
potentials stored in said first data storage and the second measured
electrode potentials stored in said second data storage;
transmitting each determined spatial distance to an intermediate storage
operatively connected to said arithmetic logic unit and supplying the
associated addresses to an intermediate address storage;
sequentially comparing by means of a comparator the spatial distances
determined between the first measured electrode potentials of said first
sample stored in said first data storage and the second measured electrode
potentials of said second sample stored in said second data storage;
determining the minimum spatial distance between the first measured
electrode potentials of said first sample and the second measured
electrode potentials of said second sample;
defining the first measured electrode potential of said first sample and
the related address associated with said minimum spatial distance as the
starting point of said preselected loop of said first one of the selected
number of individual spatial closed electrode potential patterns;
defining the second measured electrode potential of said second sample and
the related address associated with said minimum spatial distance as the
end point of said preselected loop of said first one of the selected
number of individual spatial closed electrode potential patterns; and
transmitting said first measured electrode potential and said second
measured electrode potential and the related addresses to a null address
of said measured data storage.
27. The method as defined in claim 26, further including the steps of:
repeating the steps of determining and transmitting the first and second
measured electrode potentials and the related addresses associated with
the minimum spatial distance as the starting point and as the end point
for the preselected loops of the remaining ones of the selected number of
individual spatial closed electrode potential patterns and which
preselected loops have a predetermined spatial slope value within said
predetermined acceptable spread of predetermined spatial slope values.
28. The method as defined in claim 25, further including the steps of:
storing a maximum measured electrode potential associated with the
preselected loop of the first one of said selected individual spatial
closed electrode potential pattern at a null address in said measured data
storage;
determining the spatial distances between the first measured electrode
potentials stored in said first data storage and the second measured
electrode potentials stored in said second data storage;
comparing by means of a comparator the spatial distances determined between
the first measured electrode potentials of said first sample stored in
said first data storage and the second measured electrode potentials of
said second sample stored in said second data storage with the maximum
measured electrode potential stored in said measured data storage at the
null address thereof and storing the smaller one of the two data in said
measured data storage at said null address thereof;
sequentially comparing by means of said comparator the spatial distances
determined between all of the first measured electrode potentials of said
first sample stored in said first data storage and all of the second
measured electrode potentials of said second sample stored in said second
data storage, with the datum stored in said measured data storage at the
null address thereof such that the minimum spatial distance is stored at
said null address of said measured data storage as a result of the
comparing operation;
defining the first measured electrode potential and the related address
associated with said minimum spatial distance as the starting point of the
preselected loop of said first one of the selected individual spatial
closed electrode potential patterns; and
defining the second measured electrode potential and the related address
associated with said minimum spatial distance as the end point of the
preselected loop of said first one of the selected number of individual
spatial closed electrode potential patterns.
29. The method as defined in claim 28 further including the steps of:
repeating the steps of determining the first and second measured electrode
potentials and the related addresses associated with the starting point
and with the end point of the preselected loops of the remaining ones of
the selected number of individual spatial closed electrode potential
patterns and which preselected loops have a predetermined spatial slope
value within said predetermined acceptable spread of predetermined spatial
slope values.
30. An apparatus for recording and processing a signal constituted by
measured data which vary in time and space and define a time sequence of
recurring individual spatial closed signal patterns, comprising:
a measuring unit containing a predetermined number of sensors for sensing
said signal;
a measured data storage;
said measured data storage storing the measured data and their associate
addresses and containing a null address storage at which the measured data
associated with a starting point and an end point of each said individual
spatial closed signal pattern is stored;
an analog-to-digital converter having an input side and an output side;
said analog-to-digital converter being connected on its input side to said
measuring unit and being connected on its output side to said measured
data storage;
means for determining a slope of each one of said individual spatial closed
signal patterns at a preselectable reference point and for transmitting
the measured datum and address of said preselected reference point to said
measured data storage;
a data and address bus operatively interconnecting said means for
determining said preselected reference point and said measured data
storage;
a sampling unit;
said sampling unit containing first sampling means for sampling a first
sample of measured data and their associated addresses which precede said
reference point in each one of said individual spatial closed signal
patterns;
said sampling unit further containing second sampling means for sampling a
second sample of measured data and their associated addresses which follow
said reference point in each one of said individual spatial closed signal
patterns;
said first sampling means and said second sampling means being operatively
connected to said measured data storage by means of said data and address
bus;
means for sequentially determining the spatial distance between the
measured data of said first sample and the measured data of said second
sample;
comparating means operatively connected to said means for sequentially
determining said spatial distances and comparing said spatial distances,
in order to determine a minimum spatial distance;
said comparating means being operatively connected to said measured data
storage and transferring the measured datum of said first sample which is
associated with said minimum spatial distance to said null address of said
measured data storage; and
a program sequencer operatively connected to said measured data storage,
said slope determining means, said sampling unit, and said comparating
means and controlling the slope determination, the sampling operation and
the comparating operation.
31. The apparatus as defined in claim 30, wherein:
said slope determining means and said comparating means form parts of a
common arithmetic logic unit.
32. The apparatus as defined in claim 30, wherein:
said first sampling means comprise a first data storage and a first address
storage; and
said second sampling means comprising a second data storage and a second
address storage.
33. The apparatus as defined in claim 30, wherein:
said predetermined number of sensors comprises a predetermined number of
electrodes arranged in a predetermined spatial configuration at the body
of a living being to be investigated; and
said time sequence of recurring individual spatial closed signal patterns
constituting a time sequence of recurring individual spatial closed
electrode potential patterns of a vector cardiogram. |
|
|
|
|
Claims  |
|
|
Description  |
|
|
CROSS-REFERENCE TO RELATED APPLICATION
This application is related to the commonly assigned, copending U.S.
Application Ser. No. 06/464,765, filed Feb. 7, 1983, and entitled "Method
and Apparatus for Cardiogoneometry", the disclosure of which is
incorporated herein by reference.
BACKGROUND OF THE INVENTION
The present invention relates to a new and improved method of, and
apparatus for, determining the starting point and the end point of a
spatial closed signal pattern in a time sequence of individual ones of
such spatial closed signal patterns, each of which is constituted by a
series of measuring signals.
Spatial closed signal patterns of the aforementioned type may constitute,
for example, physiological measuring signals which are picked up from a
living being by means of electrodes and such spatial closed signal
patterns occur, for example, in the as-such known methods of vector
cardiography. Such a method is described in detail in European Patent
Publication No. 0,086,429 and the aforementioned cognate U.S. Application
Ser. No. 06/464,765. In this method as well as in other known methods of
vector cardiography the starting points and the end points, for example,
of the P-, QRS- and T-loops or waves are visually determined by the
physician who must interpret the curves presented to him or her. This is
evident, for example, from "Computers in Cardiology", 1982, IEEE, page 429
et seq. entitled "Automated Vector Cardiographic Analysis by an
Inexpensive Microprocessor" (ISBN No. 0-8186-0024-1). It also follows
therefrom that the determination of the starting points and of the end
points by computation using an electronic computer tends to yield still
less reliable results than the simple visual determination.
A further possibility for determining the starting point and the end point
of a signal pattern as produced in the known vector cardiogram comprises
the steps of selecting sections from a present signal pattern in which the
signal does not or nearly does not change with time. An electrical
starting, end, or base potential can be attributed to such sections which
indicates that the starting point and the end point of the signal pattern
are located in the region of such sections. However, when such a procedure
is used, the definition of the starting point and of the end point is
still indefinite with respect to time.
The determination of the starting point and the end point of a signal
pattern is particularly difficult when the signal pattern has superimposed
thereon oscillations of a very low frequency. In a vector cardiogram, for
example, such an oscillation is effected by the breathing of the
investigated person or patient. When the vector cardiogram is recorded
under circulatory stress, such oscillations distort the signal pattern to
such a degree that the determination of the starting point and the end
point with sufficient reliability by means of the hitherto known methods
is impossible.
SUMMARY OF THE INVENTION
Therefore, with the foregoing in mind it is a primary object of the present
invention to provide a new and improved method of, and apparatus for,
determining the starting point and the end point of a spatial closed
signal pattern in a time sequence of individual ones of such spatial
closed signal patterns, each of which is constituted by a series of
measuring signals, in a manner which is not afflicted with the
aforementioned drawbacks and limitations of the hitherto known methods.
Another important object of the present invention is directed to the
provision of a new and improved method of, and apparatus for, determining
the starting point and the end point of a spatial closed signal pattern in
a time sequence of individual ones of such spatial closed signal patterns,
each of which is constituted by a series of measuring signals, in such a
manner that the moment of time associated with the starting point and the
end point is unambiguously determined.
Now in order to implement these and still further objects of the invention,
which will become more readily apparent as the description proceeds, the
method of the present development is manifested by the features that, a
predetermined number of electrodes is arranged in a predetermined
configuration at a living being to be investigated and by means of these
electrodes there is received the time sequence of individual ones of the
spatial closed signal patterns. A predetermined period of time associated
with a selected spatial closed signal pattern is subdivided into a first
time interval and a second time interval and the spatial closed signal
pattern is sampled. During this sampling operation there is determined, at
each one of a predetermined number of sampling moments associated with
said first time interval, the distance between selected ones of a
predetermined number of sampling points associated with said predetermined
number of sampling moments in said first time interval, on the one hand,
and selected ones of a predetermined number of sampling points associated
with a predetermined number of sampling moments associated with said
second time interval, on the other hand. A minimum value of the distances
between the predetermined sampling points associated with the first time
interval and the predetermined sampling points associated with the second
time interval is determined. The sampling point associated with the first
time interval and the sampling point associated with the second time
interval, between which the minimum distance exists, are respectively
defined as the starting point and the end point of the selected individual
spatial closed signal pattern.
As alluded to above, the present invention is not only concerned with the
aforementioned method aspects, but also relates to a novel construction of
an apparatus for recording a measured signal constituted by measured data
which vary in time and space and define a time sequence of recurring
individual closed signal patterns.
To achieve the aforementioned measures the inventive apparatus for
recording a signal constituted by measured data which vary in time and
space and define a time sequence of recurring individual closed signal
patterns, in its more specific aspects comprises:
a measuring unit comprising a predetermined number of sensors for sensing
said signal;
a measured data storage;
said measured data storage storing the measured data and their associate
addresses and containing a null address storage at which the measured data
associated with a starting point and an end point of each individual
closed signal pattern are stored;
an analog-to-digital converter which is connected on its input side to the
measuring unit and on its output side to the measured data storage;
means for determining a slope of each one of the individual closed signal
patterns at a preselectable reference point and for transmitting the
measured datum and address of the preselected reference point to the
measured data storage;
a data and address bus operatively interconnecting the means for
determining the preselected reference point and the measured data storage;
first sampling means for sampling a first sample of measured data and their
associated addresses which precede the reference point in each one of the
individual closed signal patterns;
second sampling means for sampling a second sample of measured data and
their associated addresses which follow the reference point in each one of
the individual closed signal patterns;
the first sampling means and the second sampling means being operatively
connected to the measured data storage by means of the data and address
bus;
means for sequentially determining the spatial distances between the
measured data of the first sample and the measured data of the second
sample;
comparating means operatively connected to the means for sequentially
determining the spatial distances and comparing the determined spatial
distances in order to determine a minimum spatial distance;
the comparating means being operatively connected to the measured data
storage and transferring the measured datum of the first sample which is
associated with the minimum spatial distance to the null address of the
measured data storage; and
a program sequencer operatively connecting the measured data storage, the
slope determining means, the first sampling means, the second sampling
means, and the comparating means and controlling the slope determination
and the sampling and comparating operations.
The advantages achieved by the invention are essentially that the magnitude
of the measured signal excursions can be exactly determined after the
moments of time associated with the starting point and the end point have
become known and therefrom also the signal magnitudes at these points have
become known. The signal magnitude at the starting point and at the end
point yields a reference magnitude. Also, different signals within a
signal pattern can be precisely delimited from each other.
In a vector cardiogram the cardiac action of a person or patient
investigated is observed by means of the temporal variations of the
electromagnetic field which is generated by the heart and which can be
represented by a vector. By means of the vector cardiogram attempts are
made to follow the direction and magnitude of the vector. For this purpose
the vector or rather its projection on a number of planes is considered.
In practice this results in a number of temporally interrelated signal
patterns. A reliable diagnosis and interpretation of the individual
signals can be obtained only when the starting point and the end point of
each individual signal of the different signal patterns are known. For the
diagnosis there are also important, in addition to the magnitude and
direction of the vector, the point of onset of the QRS-, P- and of the
T-loop or wave, the starting moment of time and the length of the
intervals therebetween.
By virtue of the inventive method and apparatus the aforementioned data can
be determined. With increasing heart beat the results which are obtained
using the hitherto known methods become more and more unreliable. The
reliability of the inventive method, however, is preserved also in these
cases of increased heart beat.
BRIEF DESCRIPTION OF THE DRAWINGS
The invention will be better understood and objects other than those set
forth above, will become apparent when consideration is given to the
following detailed description thereof. Such description makes reference
to the annexed drawings wherein:
FIG. 1 is an illustration in a predetermined plane and along a time axis of
a physiological measured signal which is picked up from a person or
patient under investigation by means of electrodes;
FIG. 2 is an illustration of the measured signal as shown in FIG. 1 in
space as well as in projection on three different planes;
FIG. 3 is a block diagram of an apparatus according to the invention for
carrying out the method illustrated in FIGS. 4a, 4b, and 4c; and
FIGS. 4a, 4b, and 4c collectively represent a flow diagram or chart
illustrating the steps of the inventive method.
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
Describing now the drawings, it is to be understood that only enough of the
inventive method and apparatus have been illustrated as needed for those
skilled in the art to readily understand the underlying principles and
concepts of the present development, while simplifying the showing of the
drawings. Turning attention now specifically to FIG. 1, there has been
shown as an example of a physiological measuring signal a section of a
vector cardiogram curve 1. Therein electrode potential values which are
picked up from an investigated person or patient by means of electrodes,
are plotted on a time axis 2. Since the inventive method will be explained
with reference to the examp1e of a vector which represents the heart
action of a living being and which continuously changes its magnitude and
direction as a function of time, the potential values illustrated in FIG.
1 can be considered as the magnitude of the vector projected into a
predetermined plane.
Such a vector or the potential values associated with its tip or end point
describes a time sequence of signal or electrode potential patterns each
of which is described by the cardiologist as comprising a QRS-loop or
wave, a T-loop or wave and a P-loop or wave. Sections 4 are interposed
intermediate these loops or waves in curve 1 and these sections 4 are
rather short and more or less indicate constant potential values.
FIG. 2 shows the vector in a triaxial coordinate system 5 defining an
orthogonal or rectangular coordinate system and illustrates the vector at
a specific moment of time by means of the arrow 6. This vector 6 starts
from a null or zero point 7 and ends at points in space which together
form the loops or waves 8, 9 and 10. The loop 8 of such vectorial
illustration is also designated as QRS-loop, the loop 9 as T-loop and the
loop 10 as P-loop. By means of the X, Y and Z axes of the coordinate
system 5 an XZ plane, an XY plane and a ZY plane are defined. The loops 8,
9 and 10 can be projected onto these three planes such that further loops
8a, 8b, 8c; 9a, 9b, 9c; and 10a, 10b, 10c can be recognized. In order to
facilitate the following explanations there are also entered individual
points 11a to 19a and 11b to 19b, along the loops 8a and 8b, respectively.
In the following there are generally described the individual steps of the
inventive method which permits the determination of the starting point and
of the end point of recurring individual spatial closed signa1 or
electrode potential patterns, specifically of, for example, a QRS-loop in
a vector cardiogram. Since the vector in each such vector cardiogram
successively describes a QRS-loop, a T-loop and a P-loop, it is important
to know, for example, at which point and at which time the QRS-loop starts
and ends because the QRS-loop gives the physician an indication with
respect to certain aspects of the cardiac action while the T-loop or the
P-loop give indications with respect to other aspects of the cardiac
action. The inventive method can be analogously employed for determining
the starting point and the end point of the P-loop or wave and of the
T-loop or wave in a vector cardiogram or the starting point and the end
point of any other recurring individual closed signal or electrode
potential pattern.
In order to obtain reliable data about the position of the starting point
20 and the end point 21 of the QRS-wave or loop, see FIG. 1, it is
essential to detect the movements of the vector and thus the QRS-loop 8,
8a, 8b, 8c in different planes. Therefore, during the preparation of a
vector cardiogram, there are periodically or continuously detected in a
manner which is known as such the values of the potential which is
represented by the vector. The graphic illustration of such potential
values, when plotted along the time axis 2, results in the curve 1 shown
in FIG. 1. The graphic illustration of such potential values, when plotted
in the XZ plane, in the XY plane, and in the ZY plane, results in the
QRS-loops 8a, 8b, and 8c | | |