A nuclear power plant includes a concrete biological shield, a metallic reactor pressure vessel surrounded by the concrete biological shield, coolant connector pieces connected to the reactor pressure vessel, coolant lines connected to the coolant connector piece, and a support engaging the coolant connector pieces and holding the reactor pressure vessel. The support includes at least one supporting tube surrounding one of the coolant connector pieces, the supporting tube having an inner surface anchored on the one coolant connector piece and an outer surface anchored on the biological shield.

A reactor cavity seal and shielding system for a PWR that protects personnel from radiation during full power operation and shutdown conditions, and allows the refueling canal to be flooded while allowing access to the lower portions of the reactor well. An integral annular seal and shield is sealed to the pressure vessel and to the primary shield. The seal preferably extends horizontally from a flange on the reactor pressure vessel to an inwardly extending ledge on the primary shield, and carries a generally coextensive body of solid neutron-absorbing material. The seal may be fabricated from stainless steel, and preferably incorporates a bellows seal to accommodate thermal expansion. The shield may be silicone rubber, refractory concrete, or any solid neutron absorber.

Collagen-containing sponges comprising an absorbable gelatin sponge, collagen, and an active ingredient are disclosed as are methods of enhancing wound healing of external and internal wounds using such sponges.