A pulmonary surfactant formulation for instillation and oral application, containing at least 0.1% by weight of 2,3 -dimethoxy-5-methyl-6-decaprenyl-1,4-benzoquinone in addition to an effective amount of pulmonary surfactant and usual excipients.

An orally absorbable improved dental formulation is provided. The dental formulation includes a base to which an active component is added. The active component comprises, based on the overall weight thereof, Vitamin C in an amount between about 10 and 25 weight percent, and Co-enzyme Q-10 (or ubiquinone), in an amount between 10 and 25 weight percent, are added.

A pharmaceutical composition and method of counteracting HMG-CoA reductase inhibitor-associated elevated transaminase levels is disclosed. The method comprises the adjunct administration of an effective amount of a HMG-CoA reductase inhibitor and an effective amount of Coenzyme Q.sub.10.

The invention provides compositions and methods for the application of those compositions in order to treat biological surfaces, especially the skin. The compositions contain a ubiquinone, may include other antioxidant agents (including melatonin), and may include an abrasive. The means of application may be by rubbing the composition into the skin, by means of a transdermal patch, or by rubbing the composition into the skin followed by application of a transdermal patch. The compositions and methods are useful for treating a variety of skin conditions, including psoriasis and hyper-pigmentation, and may also be used for cosmetic purposes and the prevention of skin damage.

The present invention is a compound and method for treating and preventing periodontal disease. The compound contains a gum tissue regeneration agent, such as coenzyme Q.sub.10, and a antimicrobial agent, such as melaleuca alternifolia extract oil, mixed into a solution medium. The compound is applied to the bristles of a brush. The brush then is used to introduce the compound into any pockets that may exist between and around the teeth and gums because of periodontal disease. Once introduced into pockets between the teeth and gums, the compound has a dual effect. First, the antimicrobial agent kills any bacteria in the pockets and prevents the growth of new bacteria in the pockets. Second, the gum tissue regeneration agent promotes growth of the gums against the teeth. As a result, the size of the pockets is reduced over time until the pockets are no longer abnormal and the damage from past periodontal disease is at least partially repaired.