Pharmaceutical compositions for the treatment of skin have been prepared in a carrier which contains 40 to 60% of liquid paraffin, 40 to 60% of solid paraffin, and 0.5 to 5% of microcrystalline wax. The new carrier is especially suitable for readily oxidizable drugs such as dithranol and its derivatives. From the compositions of the invention it is possible to prepare sufficiently thin and hard, yet non-brittle sticks by means of which the drug can be applied at precisely the desired point of the skin.
This is a continuation of application Ser. No. 768,172, filed on Aug. 22, 1985 and now abandoned, which is a continuation of application Ser. No. 478,529, filed Mar. 8, 1983, also now abandoned.
Methods of retarding and reversing periodontoclasia and gingivitis and disorders of human gingiva over 60 years of age comprise topically applying to human gingiva retinoic acid in an amount effective to retard and reverse periodontoclasia and gingivitis where said amount is insufficient to be excessively irritating. An emollient vehicle, a toothpaste and a liquid rinse facilitating the same methods are included.
The invention refers to new pharmaceutical preparations for the treatment of psoriasis and condyloma acuminata, and containing podophyllotoxin in combination with a liquid triglyceride.
A formulation containing tretinoin, a gelling agent, proteinaceous material, and water is provided for the uniform topical application of tretinoin. The water-based formulation is oil- and fat-free, alcohol-free, and rich in proteinaceous material. The formulation is stable over time and is comedogenic and less irritating and drying to the skin.
