Dermatoses involving nonacne inflammatory dermatoses, infectious cutaneous diseases, and hair loss resulting from inflammation or hormonal anomalies are treated with dicarboxylic acids containing 7 to 13 carbon atoms, or certain mercapto derivatives or salts thereof.
Topical compositions in gel form for the treatment of corns and calluses comprising a 7 to 13 carbon dicarboxylic acid and a pharmaceutically acceptable carrier, are described.
Skin suffering from emotional hyperhidrosis, ichthyosis with or without keratosis, and intrinsic or photoaging wrinkling is treated with mono- or discarboxylic acids containing 4 to 18 carbon atoms, or certain mercapto derivatives, salts or esters thereof.
A completely solubilized alcohol-free topical composition of azelaic acid in a glycol base which is stable at normal temperatures and which is useful as a commercial substitute for dispersed azelaic acid preparations. The composition has a pH of 4.0 or greater thereby substantially reducing irritation.
Noninfectious inflammatory skin diseases in which bacteria or yeasts play a significant adjunctive role are treated with topical formulations of aliphatic amines containing 9 to 18 carbon atoms, and pharmaceutically acceptable salts thereof.
Stable salts of azelaic acid with polycations such as chitosan are described. The salts according to the invention are water-soluble, therapeutically more efficacious and are valuable for use as active constituents in pharmaceutical as well as cosmeceutical compositions.
