New 1-piperazinylpyrimidine derivatives, preparation thereof and application thereof in therapeutics and cosmetics. New compounds derived from 1-piperazinylpyrimidine derivatives, and their application in therapeutics and cosmetics, corresponding to the general formula: ##STR1## in which R represents an alkoxycarbonyl group containing from 1 to 3 carbon atoms in the alkoxy chain or alternatively a furoyl group, n being 0 or 1, and their addition salts with cosmetically or pharmaceutically acceptable acids.
An intermediate compound is disclosed that is useful in the preparation of a lipid-peroxidation inhibiting substance and that is selected from the group consisting of: 2,4-bis[1-adamantylamino]-6-(1-piperazinyl)pyrimidine; and 4,6-bis(1-adamantylamino)-2-(1-piperazinyl)pyrimidine; or a pharmaceutically acceptable acid addition salt thereof.
Composition for washing keratinous materials, in particular hair and/or the skin, characterized in that it contains, in an aqueous medium, at least one silicone insoluble in this medium, at least one anionic, nonionic or amphoteric detergent surfactant and at least one scleroglucan optionally treated with glyoxal.