March 12, 1991

A group of five- and six-membered heterocyclic compounds having a nitrogen in the ring and 2 to 3 hydroxyl substituents on the ring are effective inhibitory agents of human immunodeficiency virus.

2

March 12, 1991

07/249,144

September 26, 1988

514/315  

C07D   207/12   (20060101)   C07D   207/00   (20060101)   C07D   211/00   (20060101)   C07D   211/46   (20060101)   C07D   211/88   (20060101)   A61K   31/445   (20060101)   A61K   31/40   (20060101)  

CROSS-REFERENCE TO RELATED APPLICATION This is a continuation-in-part of copending application Ser. No. 136,219, filed Dec. 21, 1987, now abandoned.

514/315  

5100797 - Fucosidase inhibitors - Owned by Monsanto Company (St. Louis, MO) The synthesis of the novel fucosidase inhibitors, .beta.-L-homofuconojirimycin and related 1-.beta.-C-substituted deoxymannojirimycins, is disclosed.