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Spiro-dihydroisoindole compounds
   
Document Number
US Patent 5098925
Issued Date
March 24, 1992
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Inventors
Bare; Thomas M. (West Chester, PA)
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Abstract
The present invention relates to spiroisoindolines that are antagonists at the phencyclidine receptor of the N-methyl-D-aspartate receptor complex and which are useful when such antagonism is desired such as in the treatment of neurological disorders. The invention further provides processes for preparing the spiroisoindolines, intermediates useful for their synthesis, pharmaceutical compositions containing them, and methods for their use.
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Number of Claims:
21
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Owner
ICI Americas Inc. (Wilmington, DE)
Published
March 24, 1992
Application Number
07/650,503
Filed
February 5, 1991
US Classification
514/409   548/411
Int'l Classification
C07D   209/00   (20060101)   C07D   209/96   (20060101)   C07D   495/10   (20060101)   C07D   495/00   (20060101)  
Assistant Examiner
Attorney/Law Firm
Priority Data
Feb 08, 1990 [GB] 9002834
USPTO Field of Search
548/411   514/409  
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