WikiPatents - Community Patent Review
Create Free Account  |  License or Sell Your Patent  |  WikiPatents Marketplace  |  WikiPatents Blog
Username:  Password:  
    
Advanced Search
Method and apparatus for breast imaging and tumor detection using modal vibration analysis    
United States Patent5099848   
Link to this pagehttp://www.wikipatents.com/5099848.html
Inventor(s)Parker; Kevin J. (Rochester, NY); Lerner; Robert M. (Rochester, NY); Huang; Sung-Rung (Rochester, NY)
AbstractA system for using Doppler modulation parameters for producing an estimation of the vibration amplitude of an object under investigation is disclosed in which a low frequency vibration source is used to force the oscillation of the object under investigation and a coherent or pulsed ultrasound imaging system is utilized to detect the spatial distribution of the vibration amplitude of the object in real-time. The reflected Doppler shifted waveform generated by reflecting the ultrasound waves off of the vibrating object under investigation is used to compute the vibration amplitude and frequency of the object using two alternative methods, either on a frequency domain estimator basis or on a time domain estimator basis. The system may also be utilized for breast imaging and tumor detection. By conforming the breast to a regular geometry, exciting specific vibrational eigenmodes, and analyzing the Doppler modulation parameters, the inherent shear and longitudinal wave parameters of breast tissue can be calculated. These are useful for detection of tumors and other abnormalities.
   














 Title Information Submit all comments and votes
 
Patent Text Patent PDF Print Page Summary File History
Plain text PDF images Print Summary File History
Drawing from US Patent 5099848
Method and apparatus for breast imaging and tumor detection using modal

     vibration analysis - US Patent 5099848 Drawing
Method and apparatus for breast imaging and tumor detection using modal vibration analysis
Inventor     Parker; Kevin J. (Rochester, NY); Lerner; Robert M. (Rochester, NY); Huang; Sung-Rung (Rochester, NY)
Owner/Assignee     University of Rochester (Rochester, NY)
Patent assignment
All assignments
Publication Date     March 31, 1992
Application Number     07/608,391
PAIR File History     Application Data   Transaction History
Image File Wrapper   Patent Term   Fees
Litigation
Filing Date     November 2, 1990
US Classification     600/443 73/575 600/441 600/587
Int'l Classification     A61B 008/00
Examiner     Jaworski; Francis
Assistant Examiner     Manuel; George
Attorney/Law Firm     Dickstein, Shapiro & Morin
Address
Parent Case    
Priority Data    
USPTO Field of Search     128/660.01 128/660.05 128/661.09 128/774 128/661.07 73/575
Patent Tags     breast imaging tumor detection modal vibration analysis
   
Enter a comma (,) or semicolon (;) between multiple tag words/phrases.
Describe this patent:
 Amusing   
 Clever   
 Complex   
 Efficient   
 Historic   
 Important   
 Innovative   
 Interesting   
 Practical   
 Simple   
[no votes]
Patent WIKI

Share information and news about this patent, including information and news about the technology, inventors, company, ligation and licensing.

 References Submit all comments and votes
 
*references marked with an asterisk below are user-added references
 U.S. References
 
Add a new US reference:  
ReferenceRelevancyCommentsReferenceRelevancyComments
4853904
Pesque
367/89
Aug,1989

[0 after 0 votes]
4819649
Rogers
600/438
Apr,1989

[0 after 0 votes]
4742830
Tamano
600/455
May,1988

[0 after 0 votes]
4338948
Perez-Mendez
600/437
Jul,1982

[0 after 0 votes]
4097835
Green
367/94
Jun,1978

[0 after 0 votes]
 Foreign References
 Other References
 Market Review Submit all comments and votes
   
Market Size
Estimate the gross annual revenues of the relevant market sector:
> $10B
$5B - $10B
$2B - $5B
$500M - $2B
$100M - $500M
$10M - $100M
$1M - $10M
$500K - $1M
$100K - $500K
< $100K
[No votes]
$0
 
$0   $2.5B   $5B   $7.5B   $10B
Market Share
Estimate the percentage of the relevant market sector this invention will capture:
75% - 100%
50% - 74.99%
25% - 49.99%
10 - 24.99%
5 - 9.99%
2 - 4.99%
1 - 1.99%
< 1%
[No votes]
0.0%
 
0%   25%   50%   75%   100%
Reasonable Royalty
What percentage of gross sales should the inventor or assignee be paid?
75% - 100%
50% - 74.99%
25% - 49.99%
10 - 24.99%
5 - 9.99%
2 - 4.99%
1 - 1.99%
< 1%
[No votes]
0.0%
 
0%   25%   50%   75%   100%
Public's "Guesstimation" of Royalty Value
Market SizeN/A[No votes]
xMarket ShareN/A[No votes]
xReasonable RoyaltyN/A[No votes]

N/A

License Availablity
If you are NOT the owner or assignee, answer here:
Yes, license is available for purchase

No, license is not currently available



[No votes]
License Availablity
If you ARE the owner or assignee, answer here:
Yes, license is available for purchase

No, license is not currently available



[No votes]
Competitive Advantage
Does this invention have a significant competitive advantage over similar technologies?
Yes

No



[No votes]
Most helpful competitive advantage comment
[No comments]

Commercial Alternatives
Are there viable commercial alternatives for this invention?
Yes

No



[No votes]
Most helpful commercial alternative comment
[No comments]

 Technical Review Submit all comments and votes
 Claims Submit all comments and votes
 


What is claimed is:

1. A method for determining the elastic constants of breast tissue in order to detect the presence of tumors or other abnormalities in said tissue using Doppler shifted signals reflected from said breast tissue, comprising the steps of:

conforming the breast tissue to a predetermined regular geometry;

exciting specific vibrational eigenmodes in said breast tissue;

scanning said breast tissue with coherent radiation and receiving Doppler shifted signals reflected by said breast tissue; and

analyzing said Doppler shifted signals to derive the vibration amplitude of said breast tissue.

2. The method of claim 1, wherein said step of analyzing includes analyzing an image created by exciting said specific vibrational eigenmodes in said breast tissue.

3. The method of claim 2, wherein said image has dominant pattern spacing at the wavelengths of said vibrational eigenmodes.

4. The method of claim 1, wherein said step of scanning uses pulsed coherent radiation.

5. The method of claim 1, wherein said step of analyzing comprises forming an image of the vibration amplitude within said conformed breast tissue and analyzing said image with respect to said specific vibrational eigenmodes in said breast tissue.

6. The method of claim 1, wherein said coherent radiation is pulsed electromagnetic radiation.

7. The method of claim 1, wherein said coherent radiation is acoustic radiation.

8. A method for characterizing breast tissue by modal vibration analysis in real-time, using Doppler shifted signals reflected from said breast tissue, comprising the steps of:

conforming said breast tissue to a predetermined regular geometry;

vibrating said conformed breast tissue using a source of vibration;

impinging coherent radiation on the surface of said conformed breast tissue;

receiving said Doppler shifted signals reflected from said surface of breast tissue; and

analyzing said Doppler shifted signals to determine discrete eigenmodes and eigenfrequencies.

9. The method of claim 8, further including the step of scanning the surface of said object with said impinging coherent radiation.

10. The method of claim 8, wherein said source of vibration has a frequency of approximately 1-1000 Hertz.

11. The method of claim 8, wherein said step of analyzing is accomplished using a time domain estimator system.

12. The method of claim 8, wherein said step of analyzing is accomplished using a frequency domain estimator system.

13. The method of claim 8, wherein said step of analyzing comprises the steps of:

generating quadrature phase signals representative of said Doppler shifted signals;

deriving the phase and co-phase signals of said quadrature phase signals; and

calculating the vibration amplitude of said conformed breast tissue based upon said quadrature phase, phase and co-phase signals.

14. The method of claim 8, wherein said coherent radiation is pulsed electromagnetic radiation.

15. The method of claim 8, wherein said coherent radiation is acoustic radiation.

16. The method of claim 8, wherein said source of vibration produces one of pure tone and broad band signals.

17. A method for determining the elastic constants of soft tissue in order to detect the presence of tumors or other abnormalities in said tissue using Doppler shifted signals reflected from said soft tissue, comprising the steps of:

conforming the soft tissue to a predetermined regular geometry;

exciting specific vibrational eigenmodes in said soft tissue;

scanning said soft tissue with coherent radiation and receiving Doppler shifted signals reflected by said soft tissue; and

analyzing said Doppler shifted signals to derive the vibration amplitude of said soft tissue.

18. The method of claim 17, wherein said step of analyzing includes analyzing an image created by exciting said specific vibrational eigenmodes in said soft tissue.

19. The method of claim 18, wherein said image has dominant pattern spacing at the wavelengths of said vibrational eigenmodes.

20. The method of claim 17, wherein said step of analyzing comprises forming an image of the vibration amplitude within said conformed soft tissue and analyzing said image with respect to said specific vibrational eigenmodes in said soft tissue.

21. The method of claim 17, wherein said step of scanning used pulsed content radiation.

22. The method of claim 17, wherein the step of analyzing comprises forming an image of the vibration amplitude within said conformed soft tissue and analyzing said image with respect to said specific vibrational eigenmodes in said soft tissue.

23. A method for characterizing soft tissue by modal vibration analysis in real-time, using Doppler shifted signals reflected from said soft tissue, comprising the steps of:

conforming said soft tissue to a predetermined regular geometry;

vibrating said conformed soft tissue using a source of vibration;

impinging coherent radiation on the surface of said conformed soft tissue;

receiving said doppler shifted signals reflected from said surface of soft tissue; and

analyzing said doppler shifted signals to determine discrete eigenmodes and eigenfrequencies.

24. The method of claim 23, further including the step of scanning the surface of said soft tissue with said impinging coherent radiation.

25. The method of claim 23, wherein said source of vibration has a frequency of approximately 1-1000 Hertz.

26. The method of claim 23, wherein said step of analyzing is accomplished using a time domain estimator system.

27. The method of claim 23, wherein said step of analyzing is accomplished using a frequency domain estimator system.

28. The method of claim 23, wherein said step of analyzing comprises the steps of:

generating quadrature phase signals representative of said Doppler shifted signals;

deriving the phase and co-phase signals of said quadrature phase signals; and

calculating the vibration amplitude of said conformed soft tissue based upon said quadrature phase, phase and co-phase signals.

29. The method of claim 23, wherein said coherent radiation is pulsed electromagnetic radiation.

30. The method of claim 23, wherein said source of vibration produces one of pure tone and broadband signals.

31. A system for characterizing breast tissue, comprising:

means for conforming said breast tissue into a predetermined geometry;

a vibration source for exciting vibrational eigenmodes in said breast tissue;

a pulsed coherent energy imaging system for scanning said breast tissue and for receiving Doppler shifted signals representative of said vibrational eigenmodes reflected by said breast tissue resulting from said scanning; and

means for evaluating said vibrational eigenmodes occurring within said breast tissue.

32. The system of claim 31, wherein said vibration source produces one of pure tone and broadband signals.
 Description Submit all comments and votes
 


CROSS-REFERENCE TO RELATED APPLICATION

This application is related to United States patent application Ser. No. 07/608,389, filed concurrently herewith, and entitled METHOD AND APPARATUS FOR USING DOPPLER MODULATION PARAMETERS FOR ESTIMATION OF VIBRATION AMPLITUDE, which is commonly assigned.

BACKGROUND OF THE INVENTION

The present invention relates generally to the use of low frequency vibrations to investigate passive objects. More particularly, the present invention relates to a method of and a system for using low frequency vibrations to vibrate an object and then using high frequency wave energy reflected by an object for analyzing the vibration of the object created by the generated low frequency vibrations in order to examine the surface or cross-section of the object and to produce an image of the examined object. The pattern of vibrations produced in breast tissue and in other organs, measured as a function of position within the tissue and as a function of vibration frequency, are utilized to determine the elastic constants of the tissue.

It is frequently useful to examine passive structures or objects by means of the application of a swept frequency vibration or audio source. Structures which are typically examined in that manner for flaws include aircraft, ships, bridge trusses and other types of large structures. In addition, soft tissue can also be examined in that manner.

In the examination of such structures, the vibration sources may be temporarily mounted on exterior surfaces of, for example, ship hulls or bridge trusses, or may be placed in the interior of the structures to be examined, such as ship hulls or passenger aircraft. The interrogating wave energy is then focused on a reference point on or within the object.

Such interrogating wave energy may vary from a laser, microwave or airborne source, for use with aircraft, bridges, ships or other structures. Sonar or ultrasound sources may be utilized for underwater inspection. The vibration source of low frequency is swept over a broad frequency range so as to excite eigenmodes with relatively high vibrational amplitudes. Once an appropriate vibration frequency is found, the interrogating wave energy can then be scanned over the surface or within a cross-section of the interior for penetrating waves. The spot size or spatial resolution of the scan, depends upon the wavelength of the vibration source used and the particular apparatus used. For simply focused coherent sources, the spot size will be equal to (1.2)(wavelength) (focal length)/(aperture radius).

Since sub-millimeter wavelengths can be achieved by the instant invention using ultrasound and optical devices as interrogating wave sources, millimeter scale, spatial resolution can be achieved utilizing the present invention. Once an appropriate scan size or region of interest is selected, an image is derived from point-by-point examination of the Doppler shift of the reflection of the interrogating source back from the object. Although different prior techniques have been described which analyze vibrations using lasers or ultrasound, none of those techniques make use of externally applied vibration and point-by-point scanning using the method of the present invention, to generate a vibration image.

The method of the present invention is useful to generate an image whose intensity or color is proportional the vibration amplitude calculated by means of the inventive method, at each point on the object. That image can be inspected for modal shapes and abnormally high or low vibration amplitudes, and can also be compared with reference images obtained earlier or from well characterized analogous structures. In addition, the modal shapes at different frequencies can be analyzed to determine the elastic constants of the material. The time required for analysis of each spot utilizing the inventive method and system described herein is less than three cycles of the vibration frequency when the frequency domain estimator method is utilized and a fraction of a single vibration cycle if the time domain estimator method is utilized. Thus, those methods can be applied rapidly so as to permit real-time imaging. Because the methods are also sensitive to vibration but are stable in the presence of noise, vibrational amplitudes of less than 1/10 of a wavelength of the interrogating wave energy can be easily detected utilizing the inventive method and system.

One prior art approach to measuring amplitudes of vibration is shown in U.S. Pat. No. 4,819,649, issued Apr. 11, 1989, to Rogers et al. That patent is directed to a non-invasive vibration measurement system and method for measuring the acoustically induced vibrations within a living organism. That patent utilizes a continuous wave of high spectral purity ultrasonic beams and utilizes two separate transducers, one for transmitting and one for receiving the focused beams.

By virtue of its frequency domain processing, the device disclosed by Rogers et al. cannot produce real-time imaging. In fact, the '649 patent does not discuss imaging at all. All of the specific implementations discussed in the '649 patent relate to frequency domain techniques which are based upon the ratio of harmonic sidebands of the reflected signal, which allows the intrusion of noise elements into the reflected sample and, thus, into any analyzed signal.

The system and method disclosed in the '649 patent is also discussed in an article written by the inventors which appeared in the Journal of Vibration. Acoustics, Stress and Reliability in Design, entitled "Automated Non-Invasive Motion Measurement of Auditory Organs in Fish Using Ultrasound", Vol. 109, January 1987, pp. 55-59. That paper discloses the use of external vibration to produce an FM Doppler shift and examines, over long periods of time, the Doppler spectrum returning from a single point. It is not a real-time system. The article assumes that, using very small vibrations, the ratio of the carrier signal to the first harmonic is indicative of the vibration amplitude. Like the '649 patent, the device of Rogers and Cox disclosed in this paper is a non-scanning, slow, frequency domain method which uses the ratio of harmonic sidebands and is restricted to use with very low amplitudes.

Another approach used in the past is disclosed in an article entitled "Imaging the Amplitude of Vibration Inside the Soft Tissues for Forced Low Frequency Vibration", by Yamakoshi, Mori and Sato, published in the Japanese Journal of Medical Ultrasonics, Vol. 16, No. 3, pp. 221-229 (1989). That article discusses an imaging system which can observe the precise movements inside of soft tissues when an external vibration is applied to those tissues. While the system described in that article does scan and make vibration images, it uses frequency domain techniques which are also based on the ratio of harmonic sidebands approach which are noise sensitive. Furthermore, it is slow and not a practical real-time system and is restricted to use with small amplitudes of vibration.

Yet another approach used in the prior art is that of Pierce and Berthelot, as disclosed in Proceedings of the SPIE, Session EE. Engineering Acoustics IV: "Laboratory and Measurement Microphone", "Absolute Calibration of Acoustic Sensors Utilizing Electromagnetic Scattering from In Situ Particulate Matter", Pierce and Yves (1988). That paper describes the same FM Doppler spectrum utilized by Cox and Rogers and as described in their article discussed above. However, Pierce et al. utilize laser methods to measure the oscillation at a point. The methodology of Pierce et al. is a non-scanning, slow, frequency domain technique which again uses the ratio of harmonic sidebands and therefore suffers from the same noise sensitivity problems as do the other prior systems discussed above.

All of the known techniques can be broadly classified as utilizing the same approach to the estimation or determination of the vibrational parameters, that is, using some ratio of spectral harmonic amplitudes. Thus, they all suffer from the disadvantages of the ratio methods because they require either intensive computation or larger lookup tables of theoretical Bessel functions for comparison with the measured data. Further, ratio methods work well only when the argument of the Bessel function is small, which poses a severe limitation on the range of the estimation of the Doppler spectrum.

As a practical matter, the performance of the ratio methods is highly degraded since almost all Doppler spectra suffer from a poor signal-to-noise ratio. Additionally, a sophisticated algorithm is required to determine the best selection of the harmonic pair to be compared. The present invention, on the other hand, utilizes a simple and noise-immune method for vibration estimation or determination.

The present invention may also be utilized with soft tissue structures, such as for breast imaging or the imaging of tumors. The criterion of digital palpation for detecting such soft tissue abnormalities, namely "stiffness" or "hardness" of a "lump", is not directly related to either the ultrasound, x-ray or MRI appearance of a hard lesion. That is because stiffness refers to solid mechanical properties measured at constant or slowly varying force. However, ultrasound echogenicity relates to inhomogeneties in structure, as measured using frequency pressure waves. X-ray absorbtion is related to the density and the presence of high atomic number elements such as calcium. In magnetic resonance imaging, the image brightness is related to the proton density and spin-spin and spin-lattice relaxation processes. Thus, no in vivo modality is available which directly assesses the stiffness of a region of tissue. The instant invention directly assesses some mechanical properties of tissue and the presence of stiff inhomogeneties can be detected using low frequency vibration and the disclosed novel imaging and analysis techniques.

SUMMARY AND OBJECTS OF THE INVENTION

In view of the foregoing, it should be apparent that there still exists a need in the art for a method of and system for providing for the remote inspection of structures or soft tissues using an externally applied vibration source and which provides for the generation in real-time of an analysis of the returned signal from the object under investigation for Doppler shift properties. It is, therefore, a primary object of this invention to provide a method of and system for remotely inspecting structures and soft tissues using externally applied vibration and Doppler shift measurement which is characterized by providing an analysis on a real-time basis of the return signal of an interrogating wave for Doppler shift properties.

More particularly, it is an object of this invention to provide a remote inspection system as aforementioned which provides for an analysis of the Doppler shifted interrogation signal in order to derive the local vibration amplitude of the reflector or object under investigation as either a gray scale or color image.

Still more particularly, it is an object of this invention to provide a system for remotely inspecting objects in which the image which represents the analyzed Doppler shifted signal reflected from the object is generated by scanning the object with wave energy such as laser beams, microwaves, sonar, or ultrasound.

Another object of the present invention is to provide a system for the remote inspection of structures which is not restricted to small amplitudes and is noise insensitive.

A further object of the present invention is to provide a system for the remote inspection of objects which utilizes a time domain method which permits the real-time imaging of the vibration amplitudes produced by reflection of the object over a region of interest from as little as three samples of quadrature components in the time domain.

A still further object of the present invention is to provide a system for the remote inspection of objects in which a time domain estimator method is utilized but which provides a system which is not restricted to small vibration amplitudes and is not a ratio of harmonic sidebands estimators. Thus, the system is very flexible and noise insensitive.

Briefly described, these and other objects of the invention are accomplished in accordance with its system aspects by using a low frequency vibration source to force the oscillation of an object under investigation and a pulsed ultrasound imaging system is utilized to detect the spatial distribution of vibration amplitude of the object in real-time. Due to the different mechanical properties of the abnormal regions of the object from those of normal regions, vibration patterns of the object at different vibration frequencies are used to determine the abnormalities. A vibration source generates a source of vibrations which is fed to a pulsed or coherent ultrasound imaging device as well as being transmitted onto the object under investigation.

The reflected Doppler shifted waveform generated by reflecting the pulsed ultrasound waves off of the vibrating object under investigation is received by the pulsed ultrasound imaging device which computes the vibration amplitude and frequency of the object in order to form a vibration image. The computations use two alternative methods, either on a frequency domain estimator basis or on a time domain estimator basis. Those methods may or may not include a noise removal process, depending upon the working environment.

The results of calculations of vibration amplitude and phase from some target position are stored in a conventional scan converter which produces an image of the estimates as a function of position over the entire scan plane. Also, synchronization between the estimator systems and the vibration source may or may not be employed, depending upon the actual vibration estimation method utilized.

With these and other objects, advantages and features of the invention that may become hereinafter apparent, the nature of the invention may be more clearly understood by reference to the following detailed description of the invention, the appended claims and to the several drawings attached herein.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1 is a block diagram showing the system of the present invention;

FIG. 2 is a block diagram showing the apparatus of the present invention;

FIG. 3 is a block diagram showing the system for noise correction for the frequency domain estimation method embodiment of the present invention;

FIG. 4 is a block diagram showing the system for the time domain estimation method embodiment of the present invention;

FIG. 5 is a schematic block diagram showing the phase and co-phase signal estimation system for the time domain estimation system of FIG. 4;

FIG. 6 is schematic block diagram of additional phase processing circuitry which may be utilized in connection with the time domain processing circuitry of FIG. 4;

FIG. 7 is a schematic block diagram of successive-phase estimator circuitry which may be utilized in connection with the phase and co-phase estimation circuitry of FIG. 4;

FIG. 8 is a schematic block diagram of successive co-phase estimator circuitry which may be utilized in connection with the phase and co-phase estimation circuitry of FIG. 4;

FIG. 9 is a schematic block diagram of bi-phase estimator circuitry which may be utilized with the phase and co-phase estimation circuitry of FIG. 4;

FIG. 10 is schematic block diagram of 1-shift cross-phase estimator circuitry which may be utilized with the phase and co-phase estimation circuitry of FIG. 4;

FIG. 11 is schematic block diagram of the phase-ratio estimator circuitry for vibration frequency estimation for use as part of the circuitry of FIG. 4;

FIG. 12 is a schematic block diagram of the auto-correlation estimator circuitry which may be utilized in conjunction with the circuitry of FIG. 4;

FIG. 13A is a schematic block diagram illustrating how a conventional velocity estimator can be utilized to provide an improved approximate estimation of vibration amplitude signal;

FIG. 13B is a schematic block diagram showing how a conventional variance estimator can be utilized to produce an improved approximate estimation of vibration amplitude signal;

FIG. 14 is a diagram showing the geometry of a cylinder which is utilized in discussing the present method of breast imaging using modal vibration analysis; and

FIG. 15 is a block diagram showing a method of imaging breast tissue according to the present invention.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT

Referring now to detail in the drawings wherein like parts are designated by like reference numerals throughout, there is illustrated in FIG. 1 in block diagram form the overall system of the present invention. A low frequency (approximately 1-1,000 Hertz) vibration source 100 applies a signal to the object under investigation 102 in order to cause the object under investigation 102 to begin vibrating.

An ultrasound transmitter and receiver 110 is used to generate ultrasonic radiation which is aimed at a point on or in the object under investigation. The waves reflected from the object under investigation are received by the receiver portion of the ultrasound transceiver 110 and supplied as an input to the pulse ultrasound imaging device 104. The vibration source 100 is connected to supply the same signal which is used to vibrate the object under investigation 102 to the pulse ultrasound imaging device 104. The pulse ultrasound imaging device 104 may be an ACUSON 128 Color Doppler Imager available from ACUSON, Mountain View, Calif.

The pulse ultrasound imaging device 104 receives the vibration signal generated by the vibration source 100 as well as the ultrasound reflected signals from the object under investigation and utilizes the two signals to produce the received signals 106. The received signals are input into a vibration parameter calculator 108, which may preferably be specialized real-time circuits as shown in FIGS. 3-12. Alternatively, it may be a computer, such as a Sun 3/50 workstation networked to a Sun disk server. Alternatively, a personal computer having real-time digital signal processing characteristics could be utilized in place of the Sun computer.

The vibration parameter calculator 108 generates the vibration images 112 which may be displayed by means of a color or monochrome CRT, laser or other printer or other display device 113.

The pulse ultrasound imaging device 104 is used to detect the spatial distribution of vibration amplitude in real-time. The spatial distribution of the vibration amplitude is generated by means of the vibration source 100, which may preferably be a 5" diameter woofer loudspeaker available from the Radio Shack Division of Tandy Corporation, Dallas, Tex., and others, causing the object under investigation 102 to vibrate, and the ultrasound transceiver 110, which may be a 3.5 MHz or 5 MHz array available from ACUSON.

Due to the different mechanical properties of the abnormal regions of the object under investigation 102 from those of its normal regions, vibration patterns of the object 102 at different vibration frequencies are used to reveal the abnormalities.

It should be understood that the vibration source 100 may use sound or any type of electromagnetic radiation which causes the object under investigation to vibrate. In addition, the ultrasound transmitter and receiver 110 may alternatively utilize any type of coherent, pulsed or continuous electromagnetic radiation that can be detected by the appropriate imaging device 104, for example, light waves, microwaves, etc. It is, however, necessary that both the vibration source 100 and the transmitter 110 utilize coherent radiation which can be readily detected by the imaging device 104.

As disclosed in FIG. 1, the present invention provides for the remote analysis and imaging using, for example, radar, microwaves, sonar, ultrasound, lasers, or any other type of electromagnetic radiation of vibrated structures such as airplanes, bridges, ship hulls or tissue, to detect flaws and cracks as revealed by the abnormal vibration amplitudes generated by such flaws. The stress concentrations which occur around such cracks and flaws are detected by using the Doppler techniques described herein.

The image is generated by scanning the vibrating object under investigation 102 with coherent, pulsed or continuous, focused or unfocussed wave energy such as laser, microwaves, sonar or ultrasound, and analyzing the return signal for Doppler shift properties. By using either the frequency domain estimation method shown and described in connection with FIG. 3 herein or the time domain estimation method shown and described in connection with FIGS. 4-12 herein, the Doppler shifted signal is analyzed 106 to derive the local vibration amplitude of the reflector or object under investigation 102. The result, when combined with information regarding the position of the interrogated object 114 is vibration images 112, which can be displayed as either a gray scale or a color image.

In general, the method of the present invention for the examination of a passive structure requires the application of a swept frequency vibration or audio source, such as the vibration source 100. In examining a passenger aircraft, for example, that may be accomplished by placing a bank of loud speakers in the interior. Vibration sources may also be temporarily mounted on exterior surfaces, such as the wings, hulls of a ship or bridge trusses. The interrogating wave energy generated, for example, by the ultrasound transceiver 110, is then focused on a reference point or within the object. The vibration source 100 is swept over a broad frequency range so as to excite eigenmodes of the object under investigation 102 with relatively high vibrational amplitudes.

Upon finding an appropriate vibration frequency, the interrogating wave energy is scanned over the surface or within a cross-section of the interior of the object under investigation 102 for penetrating waves. The time required for analysis of each spot is less than three cycles of the vibration frequency when the vibration parameter calculator 108 is utilizing the disclosed frequency domain estimator method and a fraction of a single vibration cycle where the vibration parameter calculator 108 is utilizing the time domain estimator method disclosed herein.

The spot size, or spatial resolution of the scan produced by the transceiver 110, depends upon the wavelength used and the particular apparatus. For simply focused coherent sources, it has been found that the spot size will be equal to (1.2)(wavelength)(focal length)/(aperture radius). Since the present invention achieves the use of sub-millimeter wavelengths using ultrasound and optical devices, millimeter scale spatial resolution is achieved. Also, vibrational amplitudes of less than 1/10th of one wavelength of interrogating wave energy can be easily detected utilizing the estimation methods in the vibration parameter calculator 108.

Upon selecting a scan size or region of interest, an image is derived from a point-by-point examination of the Doppler shift in the wave energy reflected by the vibrating object under investigation 102. The image intensity or color is proportional to the vibration amplitude calculated by means of the estimation method which will be described later herein, at each point of the object 102. That image can be inspected for modal shapes as well as abnormally high or low vibration amplitudes, and can also be compared with reference images obtained earlier or from well characterized analogous structures.

Referring now to FIG. 2, there is shown a block diagram of the apparatus of the present invention. As shown in that figure, the object under investigation 102 is vibrated by a vibration transducer 214 which is powered by an amplifier 216. The amplifier 216 is driven by a vibration function generator or vibration source 100 whose frequency and signal shape are adjustable. After the vibration of the object under investigation 102 has been accomplished, it is scanned by means of an ultrasound transmitter/receiver 110 which is controlled by a transmit signal generator 200 and a transmit/receive switch 202.

The transmitter/receive switch 202 functions to control the mode of operation of the ultrasound transmitter/receiver 110, that is, to place it either in the transmit or receive mode. The transmit/receive switch 202 causes the ultrasound transmitter/receiver 110 to be in the transmit mode while it is receiving a transmit signal from the transmit signal generator 202. If it is not receiving a signal from the transmit signal generator 202, the transmit/receive switch 202 causes the ultrasound transmitter/receiver 110 to be in the receive mode and it functions to transmit the Doppler echo signal received by the ultrasound transmitter/receiver 110 to the received signal amplifier 204.

The output from the received signal amplifier 204 is fed to both a detector 206 and to the beta estimators 220, alternative embodiments of which are shown in more detail in FIGS. 4-12. The output from the detector 206 is fed to a logrithmic amplifier 208 whose output is in turn fed to the storage and scan converter 210. The output from the beta estimators circuitry 220 is likewise fed to the storage and scan converters circuitry 210. The output from the storage and scan converters 210 is the vibration images which are displayed on the display 113.

A timing and position control circuit 212 produces a timing and position control signal which is used to control the vibration function generator 100. A synchronization signal generator 218 receives the output signal from the vibration function generator 100 and generates a synchronization signal S which is fed to both the beta estimator circuitry 220 and the storage and scan converters circuitry 210, as well as the timing and position control circuitry 212. The timing and position control circuitry is also connected to control the transit signal generator 200, the transmit/receive switch 202, the received signal amplifier 204, the detector 206, the logrithmic amp 208, the storage and scan converter circuitry 212 and the beta estimator circuitry 220.

A conventional ultrasound B-scan color Doppler imaging instrument, such as that manufactured by ACUSON described above, includes the equivalent of the transmit signal generator 200, the transmit/receive switch 202, the received signal amplifier 204, the detector 206, the logrithmic amplifier 208, the storage and scan converter circuitry 210, the display 113 and the timing and position control circuitry 212.

Such a conventional ultrasound imaging instrument may be utilized with the following modifications. A vibration transducer 214 is added. A synchronization signal generator 218 generates a synchronization signal based upon the output from the vibration function generator 100 which is fed to the beta estimator circuitry 220 and the storage and scan converter circuitry 210. The synchronization signal consists of information relating to the phase and frequency characteristics of the vibration function generator 100. Those characteristics are used in the calculations performed by the beta estimator circuitry 220 in order to produce the beta estimators. The estimate of beta is stored, together with the conventional ultrasound received signal amplitude in the storage and scan converters circuits 210, which outputs the information collected over the entire scan plane as a video signal of the vibration images to the display 113.

It should be noted that the output from the storage and scan converter circuitry 210 can be two separate images, such as a conventional ultrasound image and a separate image of the variations in beta over the scan plane. Or, the output from the storage and scan converter circuitry 210 may be a signal image with color overlay that can be used to display the beta (vibration) information overlaid on conventional gray scale ultrasound images.

FIG. 3 shows the operation of the frequency domain estimation method of the present invention which may be used in conjunction with the vibration parameter calculator 108 or beta estimator circuitry 220 to affect the remote analyzing and imaging of the object under investigation 102. The operation of the frequency domain estimation method is based upon the fact that the Doppler spectrum of echoes of a sinusoidally vibrating scatterer (object under investigation 102) contains discrete spectral lines weighted by Bessel functions of the first kind. The frequency domain estimation method is based upon the use of a new and simple relationship between the spread or variance of the Doppler spectrum of the echoes and the vibration amplitude of the scatterer.

The frequency domain estimation method for use with the remote inspection and analyzing system produces high accuracy even under conditions when the signal-to-noise ratio of the Doppler spectrum return from the scatterer is poor. In addition, deviations caused by slight non-linearities of the vibration of the scatterer have been found to have little contribution to the total estimation error.

Since the scattering object 102 is caused to vibrate slowly by means of the vibration source 100 so as to produce a wavelength much larger than the geometrical dimensions of the scatterer itself, the Doppler spectrum of the signals returning from essentially sinusoidally oscillating structures is similar to that of a pure tone frequency modulation (FM) signal. That spectrum is a Fourier series having spectral lines lying above and below the carrier frequency. The space in between the spectral harmonics is equal to the vibration frequency and the amplitudes of harmonics are given by different orders of Bessel functions of the first kind. Typically, it is desirable to determine the amplitude, phase and frequency of the oscillating structure.

The FM spectrum is well known and, thus, its use in connection with determining a Doppler shift of a moving object will be discussed only briefly. When a moving object is illuminated with an incident laser, radio or acoustic wave, the detected back scattered signals from that moving object contain a frequency shift known as Doppler shift. If the scatterer is oscillating with a vibration velocity much slower than the wave speed and of a vibration frequency much less than the carrier or incident wave frequency, the spectrum of the detected scattered wave will be similar to that of a pure tone FM process since the instantaneous frequency of the scattered waves has a Doppler shift proportional to the vibration velocity. The Doppler spectral moments of the reflected signal are usually defined as: ##EQU1## where .sigma..sub..omega. is the Doppler spectral spread and thus .sigma..sub..omega..sup.2 is the variance or second moment, .omega. is the mean frequency shift of the Doppler spectrum (i.e., the first moment), and S(.omega.) is the Doppler power spectrum.

Since the object under investigation 102 is vibrating, the Doppler power spectrum can thus be written as: ##EQU2## where W.sub.L is the low frequency vibration frequency and where the power spectrum is down shifted to a zero frequency, using, for example, quadrature detection. For this particular Bessel spectrum, the mean frequency w is 0 and the power spectrum is therefore symmetric about a 0 frequency. The zeroth moment only has been noted by Watson in his Treatise on the Theory of Bessel Functions, Chapter 2, pp. 14-15, 31, The MacMillan Company, New York, N.Y. (1945) as: ##EQU3##

The second moment can be derived in a similar way to obtain the result of: ##EQU4##

In general, all moments of the Bessel spectrum can be calculated from the generating function of the Bessel function given by Watson on page 14, equation (1) of his Treatise. By taking the first through kth derivative of the generating function with respect to z and substituting z=1 into the resulting expressions, all moments of the Bessel spectrum as functions of the parameters can then be calculated from the lower order moments by squaring and simple algebraic manipulation.

Approached from that point of view, the Bessel spectrum becomes a one parameter function. Therefore, the second moment is a good estimator of the spectrum itself. Thus, the vibration amplitude can be estimated from the Doppler spectral spread as: ##EQU5## The above new algorithm indicates that the amplitude parameter beta can be estimated from the standard deviation of the power spectrum.

Even utilizing the above equation, noise still presents a problem in providing a correct parameter estimation. For example, the Doppler signals tend to be 30-50 dB lower than the carrier in many applications. Thus, the signal-to-noise ratio for Doppler signals is usually poor. Therefore, it is necessary to remove stationary and uncorrelated noise from the Doppler spectral spread vibration estimator method result. The signal-to-noise ratio SNR can thus be represented by the ##EQU6## where m.sub.O,N is the zeroth moment of the noise.

As long as the noise is stationary, the moments of the noise power spectrum can be estimated or determined when the vibration is removed or halted. Once the noise moments have been estimated, the noise-free vibrational Doppler spectral spread can then be determined from the noisy signal as: ##EQU7## Even in some applications in which the vibration is inherent and cannot be controlled externally, the noise compensation can be performed by estimating the signal-to-noise ratio as well as the Doppler spectral spread of the noise from the finite band with white noise. Even if the noise is not white, the noise compensation can still be provided as long as the noise power and noise spectral spread can be estimated by statistical techniques.

The method for applying the frequency domain estimation system is shown in FIG. 3. First, the external vibration source 100 is turned off at step 300. Then, the spectral moments estimation for noise is performed at step 302. This is done using convention