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Temperature controlled RF coagulation    

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United States Patent5122137   
Link to this pagehttp://www.wikipatents.com/5122137.html
Inventor(s)Lennox; Charles D. (Hudson, NH)
AbstractRadiofrequency medical devices for ohmic heating of tissue of a patient include a temperature sensor carried by and in thermally conductive relationship with a thermally conductive electrode. The sensor is connected for feedback to a control circuit that modulates RF power applied to the electrode according to the signal received from the temperature sensor. The control circuit and RF power supply alternate between two operating modes. In the first mode the RF power supply applies RF power to the electrode. In the second mode the control circuit senses a signal from the temperature sensor in the absence of RF signal. The control circuit compares the signal from the temperature sensor to a set value and modulates the RF power applied to the electrode in accordance with the set value.
   














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Patent Text Patent PDF Print Page Summary File History
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Inventor     Lennox; Charles D. (Hudson, NH)
Owner/Assignee     Boston Scientific Corporation (Watertown, MA)
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Publication Date     June 16, 1992
Application Number     07/515,850
PAIR File History     Application Data   Transaction History
Image File Wrapper   Patent Term   Fees
Litigation
Filing Date     April 27, 1990
US Classification     606/40 606/42 606/49
Int'l Classification     A61B 017/39
Examiner     Pellegrino; Stephen C.
Assistant Examiner     Shumaker; Steven J.
Attorney/Law Firm     Fish & Richardson
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Parent Case    
Priority Data    
USPTO Field of Search     606/33 606/34 606/35 606/36 606/37 606/38 606/39 606/40 606/41 606/47 128/736 128/804 128/399 128/400 128/401
Patent Tags     temperature controlled rf coagulation
   
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I claim:

1. A method of ohmic heating of tissue of a patient in order to induce coagulation, comprising the steps of

selecting a temperature at which target tissue is to be coagulated through flow of RF current through tissue disposed between a thermally conductive, tissue-engaging electrode and at least one other patient-contacting RF conductor, said selected temperature being a maximum temperature consistent with avoiding detrimental sticking of the electrode to the tissue directly engaged by the electrode and avoiding undesired desiccation of tissue,

repeatedly switching between a power on mode and a power off mode,

during said power on mode, applying RF power to said electrode and said at least one other conductor in order to cause RF current of a frequency in the range of about 100 kilohertz to 100 megahertz to flow between said electrode and said at least one other conductor for tissue-coagulation, said thermally conductive, tissue-engaging electrode concentrating RF current in a local region of the patient's tissue in the vicinity of said electrode,

during said power off mode, sensing, by means of a temperature sensor carried by and in thermally conductive relationship with said thermally conductive, tissue-engaging electrode, the temperature of said electrode in the absence of RF signal, thereby to sense indirectly the temperature of tissue contacted directly by the electrode, said temperature sensor having a greater accuracy in the absence of interfering RF electrical noise caused by said RF current passing through said thermally conductive electrode than in the presence of said interfering RF electrical noise,

comparing said sensed temperature to said selected, maximum temperature,

modulating said Rf power applied to said electrode in accordance with comparison of said sensed temperature and said selected, maximum temperature, and

coagulating said target tissue at said selected, maximum temperature as said modulated RF current flows between said electrode and said at least one other conductor during said power on mode.

2. The method of claim 1 wherein said temperature sensor is a thermistor.

3. The method of claim 1 wherein the period of temperature sensing is of the order of 1 percent of the cycle time.

4. The method of claim 1 wherein said at least one other conductor is a patient grounding plate.

5. The method of claim 1 wherein said thermally conductive, tissue-contacting electrode and said at least one other patient-contacting RF conductor comprise opposed electrodes each of which has a localized contact with the tissue of said patient.

6. The method of claim 5 wherein said electrodes are mounted on opposing jaws of a forceps, and said method further comprises the step of grasping tissue between said opposing jaws of said forceps.

7. The method of claim 5 or 6 wherein said step of sensing temperature comprises sensing the temperature of each of said electrodes.

8. The method of claim 7 wherein said step of modulating said RF power is performed in accordance with the higher temperature sensed during said step of sensing the temperature of each of said electrodes.

9. The method of claim 1 wherein said temperature sensor comprises a thermocouple.

10. The method of claim 1 wherein said thermally conductive, tissue-engaging electrode is mounted on a gastro-intestinal hemostasis probe, said method further comprises the step of inserting said gastro-intestinal hemostasis probe into the gastro-intestinal tract of said patient, and said step of coagulating said target tissue comprises inducing gastro-intestinal hemostasis.

11. The method of claim 1 wherein said thermally conductive, tissue-engaging electrode is located on a surgical hemostasis probe, said method further comprises the step of applying said surgical hemostasis probe to the body of said patient at a location at which surgery is being performed, and said step of coagulating said target tissue comprises inducing hemostasis in the vicinity of said surgical probe.

12. The method of claim 1 wherein said thermally conductive, tissue-engaging electrode is located on a guidewire probe.

13. The method of claim 12 wherein

said electrode comprises a tip of said guidewire probe,

said guidewire probe is coated with insulation except at said electrode tip of said probe,

said thermistor is mounted within said tip of said guidewire probe

said method further comprises the step of inserting said guidewire probe into a duct in said patient's body, and

said step of coagulating said target tissue results in thermal occlusion of said duct.

14. The method of claim 13 wherein said duct is a seminal duct and said step of coagulating said target tissue results in thermal occlusion of said seminal duct.

15. The method of claim 13 wherein said duct is a fallopian tube and said step of coagulating said target tissue comprises thermal occlusion of said fallopian tube.

16. The method of claim 1 wherein said thermally conductive, tissued-engaging electrode is located on a needle.

17. The method of claim 16 wherein

said electrode comprises a tip of said needle,

said method further comprises the step of passing said needle through the skin of said patient,

and said step of coagulating said target tissue comprises percutaneously inducing coagulation treatment of a liver metastasis.

18. The method of claim 17 wherein

said electrode comprises a tip of said needle,

and said step of coagulating said target tissue comprises inducing coagulation treatment of a prostatic tumor.

19. The method of claim 1 wherein said thermally conductive, tissue-engaging electrode is mounted on a thermal ablation probe, said method further comprises the steps of sensing electrical impulses from the heart using at least one electro-physiology electrode mounted on said thermal ablation probe and positioning said electrode at the location of a source of arrythmia, and said step of coagulating said target tissue comprises inducing coagulation of said location of said source of arrythmia.

20. The method of claim 1 wherein

said step of applying RF power to said electrode and said at least one other conductor is performed by an RF power supply having one pole connected to said electrode and a second pole connected to said at least one other conductor,

and said steps of comparing said sensed temperature to said selected, maximum temperature and modulating said RF power applied to said electrode are performed by a control circuit connected to said temperature sensor and constructed to modulate RF power applied to said electrode according to the signal received from said temperature sensor.

21. The method of claim 1 wherein

said step of selecting said maximum temperature comprises setting a reference signal,

and said step of modulating said RF power to said electrode comprises causing said temperature of said electrode to approach a temperature represented by said reference signal, thereby to control the temperature of said electrode and consequently the temperature of tissue contacted by the electrode.
 Description Submit all comments and votes
 


BACKGROUND OF THE INVENTION

This invention relates to medical devices that apply an RF electrical current to tissue of a patient in order to heat the tissue to induce coagulation.

Devices that perform localized heating of tissue may apply an RF electrical current through the tissue by means of electrical contacts. Tissue in the vicinity of an electrical contact is heated through resistance of the tissue to the electrical current. Such tissue heating devices may typically apply current having an intensity and duration that is empirically calculated to heat the tissue to a desired temperature. Nevertheless, the actual extent of heating is unpredictable. Excessive heating of the tissue can cause complete desiccation or "charring" of the tissue that surrounds one or more electrical contacts. A film of charred tissue around an electrical contact can result in a high impedance between the electrical contacts that in turn leads to a cessation of the heating process. Moreover, excessive heating of the tissue can cause an electrical contact to stick to the tissue.

SUMMARY OF THE INVENTION

The invention features a radiofrequency medical device for ohmic heating of tissue of a patient in order to induce coagulation. The device includes a plurality of RF conductors between which RF current flows for tissue-coagulation. At least one of the conductors is a thermally conductive electrode that concentrates RF current in a local region of tissue contacted by the electrode. The electrode is connected to one pole of an RF power supply. A second pole of the RF power supply is connected to the patient via a second conductor. A temperature sensor is carried by and in thermally conductive relationship with the thermally conductive electrode. The temperature sensor senses the temperature of the electrode, and thereby indirectly senses the temperature of tissue in contact with the electrode. The sensor is connected by a feedback line to a control circuit that automatically modulates RF power applied to the electrode according to the feedback signal received from the temperature sensor. The control circuit and RF power supply alternate between two operating modes. In the first mode the RF power supply applies RF power to the electrode. In the second mode the control circuit senses a signal from the temperature sensor in the absence of RF signal. The control circuit compares the signal from the temperature sensor to a set value and modulates the RF power applied to the electrode in accordance with the set value.

In preferred embodiments, the temperature sensor is a thermistor. Alternatively, the temperature sensor may be a thermocouple. The period of temperature sensing is of the order of 1 percent of the cycle time, and the frequency of the cycle is substantially greater than the frequency response of the electrode-tissue system. The set value is a user set reference signal internal to the control circuit. The control circuit modulates RF power applied to the electrode to cause the temperature of the temperature sensor to approach a temperature represented by the reference signal, thereby to control the temperature of the electrode and consequently the temperature of tissue contacted by the electrode. The second conductor is a patient grounding plate. The control circuit modulates the RF power applied to the electrode by varying intensity of the RF power rather than by disconnecting the RF power during the first mode.

In one embodiment the conductors are opposed electrodes mounted on opposing jaws of a forceps, each of which has a localized contact with the tissue of the patient. Each of the electrodes may be contacted by a temperature sensor monitored by the control circuit, the RF voltage being modulated in accordance with the higher temperature that is sensed by a respective sensor. In another embodiment the electrode is constructed for thermal ablation therapy for arrhythmias, and the thermistor is embedded into the electrode. In another embodiment the electrode is mounted on a probe for gastro-intestinal hemostasis. In another embodiment the electrode is mounted on a cautery probe. In another embodiment the electrode is the tip of a guidewire probe for thermally occluding fallopian tubes or seminal ducts. The guidewire probe is coated with insulation except at a tip of the probe, and the thermistor is mounted in the tip of the guidewire probe. In another embodiment the electrode is the tip of a needle for percutaneous electrode coagulation treatment of liver metastases or for transrectal electrode coagulation treatment of prostatic tumors.

The invention provides a new, feedback-controlled, time-sharing way of