A sheet material comprising discrete depressions which are at least partially filled with micronized medicament and which are useful as or in a drug delivery device. This sheet material is useful in devices which provide for aerosolization of the medicament, for delivery to a patient by inhalation.
A recording material having a resin layer containing a polyester resin as a main component on a support, the recording material is disclosed in having (A) a groove or grooves placed continuously or intermittently extending linearly with a depth not less than 45% but not more than 90% of the thickness of the recording material, or (B) linearly continuous holes wherein width of the holes is not less than 15.multidot.m and not more than 130.multidot.m, length of the holes is not less than 50.multidot.m and not more than 500.multidot.m, and interval between the holes is not less than 30.multidot.m and not more than 300.multidot.m. In use of this recording material, printed items in a desired size can be formed rapidly and easily.
The present invention is a process for the production of covered tablets by melt calendering in which the melt containing active ingredient is introduced between two sheets of the covering material into the molding rolls.
A refillable medical device comprising a base unit (4) adapted to be engaged with a refill unit (2), the device comprising means for counting the number of different refill units which are engaged with the base unit (4). The device may be in the form of a dry powder or pressurised aerosol inhaler, needleless injector, intravenous drip system etc. The device may comprise means to disable the device after a predetermined number of refill units have been used with the base.
A breath-actuated dry powder medicament inhalator device having a housing and a conduit mounted within the housing defining an air passageway therethrough having an aperture in the sidewall thereof. A blister-type strip of sealed containers arranged in a matrix of rows and columns wherein the columns extend generally diagonally to the longitudinal axis of the strip is secured in a two-piece cage adapted for being rotatably mounted around the conduit of the inhalator device. Advancement means are provided for rotatably moving the two-piece cage and blister strip contained thereby in a generally helical pathway relative to the conduit so as to successively advance each of the sealed containers of the blister strip into registration with the conduit aperture. Piercing means are associated with the housing for successively piercing each of the sealed containers of the blister strip when advanced into registration with the conduit aperture by the advancement means in order to introduce the dry powder compound contained therein into the air passageway of the conduit.
