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Catheter system for controllably releasing a therapeutic agent at a remote tissue site    

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United States Patent5470307   
Link to this pagehttp://www.wikipatents.com/5470307.html
Inventor(s)Lindall; Arnold W. (1150 Nordic Ave. North, P.O. Box 187, Stillwater, MN 55082)
AbstractA catheter having a therapeutic agent chemically bonded to a substrate on its exterior surface using a linker which photolytically releases the agent upon exposure to light energy at an appropriate wavelength. The linker is attached to the substrate via a complementary chemical group, with the opposing end containing an aromatic ring with a nitro group in the ortho position relative to a methyl or ethyl group which is functionalized to accept a complementary bond to the therapeutic agent. The substrate may include materials such as glass, polyamide, polyester, polyolefin, polypropylene, polyurethane, or latex. The therapeutic agent may include peptides, proteins, steroids, carbohydrates, nucleotides, or other aliphatic or heterocyclic products, and may be bonded to a molecular lattice or meshwork to accommodate a high molecular concentration per unit area and the inclusion of ancillary compounds such as markers or secondary emitters.
   














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Patent Text Patent PDF Print Page Summary File History
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Inventor     Lindall; Arnold W. (1150 Nordic Ave. North, P.O. Box 187, Stillwater, MN 55082)
Owner/Assignee    
Patent assignment
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Company News
Publication Date     November 28, 1995
Application Number     08/214,051
PAIR File History     Application Data   Transaction History
Image File Wrapper   Patent Term   Fees
Litigation
Filing Date     March 16, 1994
US Classification     604/20 600/339 604/28 604/265 604/890.1
Int'l Classification     A61M 001/00
Examiner     Rosenbaum; C. Fred
Assistant Examiner     Van Over; Perry E.
Attorney/Law Firm     Briggs and Morgan
Address
Parent Case    
Priority Data    
USPTO Field of Search     604/20 604/28 604/264 604/265 604/266 604/890.1 604/891.1 604/892.1 604/92 604/93 604/264 604/265 604/266 604/83 604/113 604/264 604/265 604/266 604/57 604/264 604/265 604/266 128/633 128/634 128/898 128/DIG. 3 606/7 606/194 607/92
Patent Tags     catheter controllably releasing therapeutic agent a remote tissue site
   
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