Alkoxylated phenyl and coumarin derivatives useful in the treatment of viral infections are disclosed. The compounds are particularly useful in the treatment of picornaviruses, and more particularly in the treatment of rhinoviruses.
The invention provides the use of flavin compounds such as cirsiliol, 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment of infections, particularly for viral (e.g., HCV, HIV, a picornavirus genus virus or a respiratory virus) or parasite (e.g., toxoplasmosis) infections. Also provided are compositions for use in the methods.