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Apparatus for removing components from solutions    
United States Patent5496471   
Link to this pagehttp://www.wikipatents.com/5496471.html
Inventor(s)Heyl; Barbara L. (Atlanta, GA); Winterton; Lynn C. (Roswell, GA); Su; Kai C. (Alpharetta, GA); White; Jack C. (Stone Mountain, GA)
AbstractA dispensing device having a container body defining a solution retaining chamber therein, the container having an outlet for dispensing the solution from the chamber and means for removing a component from the solution as the solution is dispensed from the chamber through the container outlet. A method is provided for administering to a patient a pharmacologically active substance which substance is stable only at a pH value which is extreme in the acidic or alkaline region and at which pH value the substance cannot be administered without causing discomfort and/or injury to the patient. The substance is maintained in a solution or dispersion at the pH at which it is stable until the time of administration. At this time the substance is administered through a chamber containing an ion exchange resin which changes the pH of the solution or dispersion to a value which will not cause discomfort and/or injury to the patient.
   














 Title Information Submit all comments and votes
 
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Drawing from US Patent 5496471
Apparatus for removing components from solutions - US Patent 5496471 Drawing
Apparatus for removing components from solutions
Inventor     Heyl; Barbara L. (Atlanta, GA); Winterton; Lynn C. (Roswell, GA); Su; Kai C. (Alpharetta, GA); White; Jack C. (Stone Mountain, GA)
Owner/Assignee     Ciba-Geigy Corporation (Ardsley, NY)
Patent assignment
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Publication Date     * March 5, 1996
Application Number     08/024,224
PAIR File History     Application Data   Transaction History
Image File Wrapper   Patent Term   Fees
Litigation
Filing Date     March 1, 1993
US Classification     210/266 210/282 222/190 222/212 222/420
Int'l Classification     B01D 015/04
Examiner     Cintins; Ivars
Assistant Examiner    
Attorney/Law Firm     Wenderoth, Lind & Ponack
Address
Parent Case     This application is a continuation-in-part of now abandoned application Ser. No. 07/873,215, filed Apr. 24, 1992 which is a continuation-in-part of now abandoned application Ser. No. 814,728, filed Dec. 19, 1991, which application is a division of application Ser. No. 671,967, filed Mar. 18, 1991 (now U.S. Pat. No. 5,080,800), which is a division of application Ser. No. 461,988, filed Jan. 8, 1990 (now U.S. Pat. No. 5,056,689).
Priority Data    
USPTO Field of Search     210/266 210/282 210/289 222/189 222/190 222/212 222/420
Patent Tags     removing components solutions
   
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 Technical Review Submit all comments and votes
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What is claimed is:

1. A device for dispensing an ophthalmic solution, comprising:

(a) a container body defining a solution retaining chamber therein, said chamber containing an ophthalmic solution containing a pharmacologically active substance and having a first pH, said container having an outlet for dispensing the solution from the chamber; and

(b) means for changing the pH of the solution as the solution is dispensed from the chamber through the outlet.

2. The device of claim 1, wherein the pH changing means comprise an ionic exchange material provided within the path of the solution as the solution travels from the chamber to the outlet.

3. The device of claim 2, and further comprising a dispensing head on the container having passage means therethrough, the passage means having a first end in communication with the chamber and a second end being the outlet, the pH changing means located intermediate the first end and the outlet.

4. The device of claim 3, wherein the dispensing head is integrally formed on the container body.

5. The device of claim 3, and further comprising means for maintaining the ionic exchange material in position within the passage means.

6. The device of claim 5, wherein the means for maintaining the ionic exchange material in position within the passage means comprise a first supporting member located over the first end of the passage means and a second supporting member located over the second end of the passage means, the ion exchange material being held between the first and second porous members.

7. The device of claim 6, wherein the first supporting member is comprised of a sponge-like material to act as means for compensating for changes in size of the ionic exchange material during the dispensing of the solution.

8. The device of claim 3, and further comprising means for compensating for changes in size of the ionic exchange material during the dispensing of the solution.

9. The device of claim 8, wherein the size change compensating means comprise sponge-like material located within the passage means.

10. The device of claim 2, wherein the ionic exchange material is an anionic exchange material for raising the pH of the solution as the solution is dispensed from the chamber through the outlet.

11. The device of claim 2, wherein the ionic exchange material is a cationic