February 11, 1997

A method of treatment or prophylaxis of angina in mammals, such as humans, which comprises the administration to the sufferer of an effective amount of a compound of formula (I), or a pharmaceutically acceptable salt thereof, or a solvate of any of the foregoing: ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, A and B are herein defined.

3

February 11, 1997

08/458,046

June 1, 1995

514/478   514/522 514/561 514/564 514/821 558/416 560/27

C07C   275/00   (20060101)   C07C   275/34   (20060101)   A61K   31/135   (20060101)   A61K   31/16   (20060101)   C07D   213/00   (20060101)   C07D   317/62   (20060101)   C07D   213/74   (20060101)   C07D   317/00   (20060101)  

CROSS-REFERENCE This is a division of Ser. No. 845,522 filed Mar. 4, 1992, now abandoned.

Feb 15, 1986 [GB] 8603765 U

564/367   514/619   514/620   514/561   514/564   514/478   514/522   514/821   560/27   558/416