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| United States Patent | 5653939 |
| Link to this page | http://www.wikipatents.com/5653939.html |
| Inventor(s) | Hollis; Mark A. (Concord, MA), Ehrlich; Daniel J. (Lexington, MA), Murphy; R. Allen (Boxboro, MA), Kosicki; Bernard B. (Acton, MA), Rathman; Dennis D. (Ashland, MA), Chen; Chang-Lee (Sudbury, MA), Mathews; Richard H. (Chelmsford, MA), Burke; Barry E. (Lexington, MA), Eggers; Mitch D. (The Woodlands, TX), Hogan; Michael E. (The Woodlands, TX), Varma; Rajender Singh (The Woodlands, TX) |
| Abstract | A method and apparatus are disclosed for identifying molecular structures
within a sample substance using a monolithic array of test sites formed on
a substrate upon which the sample substance is applied. Each test site
includes probes formed therein to bond with a predetermined target
molecular structure or structures. A signal is applied to the test sites
and certain electrical, mechanical and/or optical properties of the test
sites are detected to determine which probes have bonded to an associated
target molecular structure. |
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Title Information  |
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| Inventor |
Hollis; Mark A. (Concord, MA) , Ehrlich; Daniel J. (Lexington, MA) , Murphy; R. Allen (Boxboro, MA) , Kosicki; Bernard B. (Acton, MA) , Rathman; Dennis D. (Ashland, MA) , Chen; Chang-Lee (Sudbury, MA) , Mathews; Richard H. (Chelmsford, MA) , Burke; Barry E. (Lexington, MA) , Eggers; Mitch D. (The Woodlands, TX) , Hogan; Michael E. (The Woodlands, TX) , Varma; Rajender Singh (The Woodlands, TX) |
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| Publication Date |
August 5, 1997 |
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| Filing Date |
August 7, 1995 |
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| Parent Case |
RELATED APPLICATIONS
This application is a divisional of co-pending application Ser. No.
07/872,582 filed Apr. 23, 1992, which is Continuation-in-Part of U.S. Ser.
No. 07/794,036, filed Nov. 19, 1991 now abandoned and entitled METHOD AND
APPARATUS FOR MOLECULE DETECTION. |
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Title Information |
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