Compounds having both calcium antagonist and antioxidant activity are disclosed. The compounds are useful in preventing or alleviating damage to tissues at the cellular level. Methods of treatment which employ these properties of the compounds and corresponding pharmaceutical compositions are also disclosed.
A method for treatment of light-injured retinal degeneration disease comprising, administering an effective amount of a dihydropyridine calcium antagonist other than nimodipine is provided. The dihydropyridine calcium antagonist used in the present invention is useful for treatment of light-injured retinal degeneration, especially macula lutea degeneration including age-related macula degeneration.
