March 17, 1998

The present invention relates to certain novel triaryl methyl free radicals and their use as image enhancing agents in magnetic resonance imaging (MRI) as well as to contrast media containing such radicals and to the use of such radicals and their non-radical precursors in the manufacture of MRI contrast media.

7

March 17, 1998

08/467,273

June 6, 1995

424/9.3   549/31

C07B   61/02   (20060101)   C07B   61/00   (20060101)   C07D   493/04   (20060101)   C07D   497/00   (20060101)   C07D   495/04   (20060101)   C07D   495/00   (20060101)   C07D   497/04   (20060101)   C07D   493/00   (20060101)   A61K   49/20   (20060101)   A61K   49/06   (20060101)   C07D   519/00   (20060101)   C07F   7/08   (20060101)   C07F   7/00   (20060101)  

CROSS REFERENCE TO RELATED APPLICATION This application is a continuation-in-part of application Ser. No. 08/220,522, filed Mar. 31, 1994 now U.S. Pat. No. 5,530,140.

Apr 02, 1993 [GB] 93-07027.4

549/31   424/9.3  

6063360 - Free radicals comprising benzodithiole derivatives - Owned by Nycomed Imaging A/S (Oslo,NO) The present invention relates to certain novel triaryl methyl free radicals and their use as image enhancing agents in magnetic resonance imaging (MRI) as well as to contrast media containing such radicals and to the use of such radicals and their non-radical precursors in the manufacture of MRI contrast media.

6013810 - Free radicals - Owned by Nycomed Imaging AS (Oslo,NO) Novel triarylmethyl free radicals, their use as image enhancing agents in MRI, in particular to their use in Overhauser enhanced MRI of a sample for determining oxygen concentration of said sample.