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Therapeutical method for treating chronic arteriosclerosis obliterans
   
Document Number
US Patent 5811457
Issued Date
September 22, 1998
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Abstract
A therapeutical method for treating chronic arteriosclerosis obliterans in particularly selected patients with severely disabling intermittent claudication is disclosed, which comprises administering propionyl L-carnitine or a pharmacologically acceptable salts thereof.
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Number of Claims:
10
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Published
September 22, 1998
Application Number
08/714,424
Filed
September 16, 1996
US Classification
514/547  
Int'l Classification
A61K   31/21   (20060101)   A61K   31/221   (20060101)  
Priority Data
Mar 04, 1996 [EP] 96830093
USPTO Field of Search
514/547  
Related Patents
7560485 - Method for treating intermittent claudication comprising the administration of propionyl L-carnitine and a concomitant physical training - Owned by SIGMA-TAU Industrie Parmaceutiche Riunite S.p.A. (Rome,IT)

The present invention discloses a method for treating a subject suffering from intermittent claudication (IC) wherein said subject takes an effective dose of propionyl L-carnitine or a pharmaceutically acceptable salt thereof and also engaging in a concomitant physical training program. The method is particular effective for patients with intermittent claudication at class II of the Leriche-Fontaine's classification. The method provides a relief from peripheral arterial disease symptoms, as shown by claudication-limited exercise tolerance, while also improving quality of life.

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