A method for preventing and/or treating heart failure and ventricular dysfunction in a warm blooded animal comprising administering to the warm blooded animal a therapeutically effective amount of endothelin antagonists described herein.
A composition for preventing and/or treating heart failure and ventricular dysfunction in a warm blooded animal comprising a therapeutically effective amount of an endothelin antagonist of the formula: ##STR1## is disclosed
A method for preventing and/or treating heart failure and ventricular dysfunction in a warm blooded animal comprising administering to the warm blooded animal a therapeutically effective amount of an endothelin antagonist of the formula: as defined herein.
The present invention relates to a cyclopentenopyridine derivative represented by general formula (I) or a pharmaceutically acceptable salt thereof, wherein Ar is a phenyl group or the like. R.sup.1 is a mono- or di-C.sub.1 -C.sub.6 alkylamino group or the like, and R.sup.2 is a hydroxyl group or the like, a process for its production and its use. ##STR1##
