A method of treating or preventing a disorder resulting from a mitochondr dysfunction induced by an iron overload including Friedreich Ataxia, hypertrophic cardiomyopathy, Hallervorden-Spatz disease, sideroblastic anemia by administering an effective amount of an ubiquinone derivative such as idebenone, decylubiquiqnone, coenzyme Q2, coenzyme Q4, and coenzyme Q6, either alone or in conjunction with a second therapeutic agent or a non-reducing antioxidant.
A regenerative or protective topical skin preparation includes idebenone (6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzochinol) or a derivative of idebenone.
