Water-in-oil-in-water multiple emulsion compositions are disclosed. The multiple emulsion compositions comprise an external aqueous phase optionally incorporating a surfactant system capable of forming liquid crystals as an emulsifier. The internal phase comprises a primary water-in-oil emulsion, wherein the primary emulsion comprises a first topically-active compound, a surfactant phase, an oil phase, and water.
CROSS-REFERENCE TO RELATED APPLICATION
This application is a continuation of U.S. patent application Ser. No. 08/349,904, filed Dec. 6, 1994, now U.S. Pat. No. 5,565,280 issued Aug. 12, 1997.
Pumpable multiple phase compositions for carrying agents and components downhole and controllably releasing them by breaking the suspensions are described. The multiple phase composition may have an external or third phase, which in turn has a first pumpable emulsion internally. The first pumpable emulsion has a second phase containing a first phase which bears the agent to be controllably released. The entire pumpable multiple phase composition may thus be an oil phase-in-aqueous phase-in-oil phase emulsion, or an aqueous phase-in-oil phase-in-aqueous phase emulsion. For example, a water-soluble shale stabilizer could be delivered downhole in an aqueous phase-in-oil phase-in-aqueous phase multiple phase emulsion by injecting the multiple phase composition into a water-based drilling fluid, and then the suspension broken by rotary bit nozzles under high shear stress to release the shale stabilizer at the drilling zone.
Nimesulide topical formulations are provided in the form of liquid crystals. The emulsifier cetylstearyl glycoside is used, and constituents of the lipid phase such as caprylic/capric triglycerides and jojoba oil, consistence factors such as cetylstearyl alcohol. Also disclosed is a process for the preparation thereof. The formulations have advantages such as higher stability, better release and absorption of nimesulide, and a higher bioavailability of the active ingredient.
A method for permanently dyeing hair which comprises subjecting said hair to a number of treatments, having a set time interval between each two consecutive such treatments, wherein each treatment comprises steps a.) and b.) below: a.) contacting said hair, for a period of about 5 seconds to about 5 minutes with a recently made mixture of: i) part ai dye intermediates in water at alkaline pH with quaternary ammonium compounds; ii) part aii an oxidizing compound such as hydrogen peroxide in water at acidic pH; b.) rinsing said mixture from said hair with water; and wherein said number of treatments is between about 2 to about 30; and wherein said set time interval between each two consecutive treatments is between about 8 hours and 30 days.
Pumpable multiple phase compositions for carrying agents and components downhole and controllably releasing them by breaking the suspensions are described. The multiple phase composition may have an external or third phase, which in turn has a first pumpable emulsion internally. The first pumpable emulsion has a second phase containing a first phase which bears the agent to be controllably released. The entire pumpable multiple phase composition may thus be an oil phase-in-aqueous phase-in-oil phase emulsion, or an aqueous phase-in-oil phase-in-aqueous phase emulsion. The agent may be released by one or more of a variety of mechanisms. For example, a water-soluble shale stabilizer could be delivered downhole in an aqueous phase-in-oil phase-in-aqueous phase multiple phase emulsion by injecting the multiple phase composition into a water-based drilling fluid, and then the suspension broken by rotary bit nozzles under high shear stress to release the shale stabilizer at the drilling zone. The multiple phase emulsion compositions of this invention may also be used to deliver agents to remote locations along a conduit.
A brightly colored composition that me be quickly applied to a person's skin to increase their visibility while exercising or travelling by foot, bicycle, or the like. The composition includes a base carrier medium such as a lotion, cream, gel or the like having a coloring agent dissolved or otherwise dispersed therein. The composition also includes an antiperspriant to minimize degradation due to excessive sweating while exercising.
