or
Bookmark and Share
Method for the treatment of fibroproliferative disorders by application of inhibitors of protein hydroxylation
   
Document Number
US Patent 5965586
Issued Date
October 12, 1999
Link
Map
Abstract
The present invention relates to a method of treating a patient with a fibrotic or fibroproliferative disorder and a method of suppressing formation of collagen and collagen-like substances or biosynthesis of procollagen in living systems by administering to a patient or living system, respectively, an effective amount of a compound of Formulae (I) or (II) and derivatives thereof: ##STR1## R.sub.1, R.sub.2, R.sub.3, and R.sub.4 each individually represent a hydrogen, an alkyl, alkenyl, or alkoxy group containing 1 to about 8 carbon atoms, an aryl, aralkyl, or cycloalkyl group containing about 5 to 12 carbon atoms, or a carboalkoxy or carbamyl group containing up to 8 carbon atoms, or a peptide or peptidomimetic moiety containing 10 to about 30 carbon atoms.
Drawing
Method for the treatment of fibroproliferative disorders by application of inhibitors of protein hydroxylation - US Patent 5965586 Drawing
Drawing from US Patent 5965586
Tags:
Description:
Amusing 0%
Clever 0%
Complex 0%
Efficient 0%
Historic 0%
Important 0%
Innovative 0%
Interesting 0%
Practical 0%
Simple 0%
Number of Claims:
27
Comments:
no comments yet
Published
October 12, 1999
Application Number
08/991,758
Filed
December 16, 1997
US Classification
514/348   514/2
Int'l Classification
A61K   31/4422   (20060101)   A61K   31/4412   (20060101)   C07K   5/02   (20060101)   C07K   5/00   (20060101)   A61K   31/00   (20060101)  
Examiner
Attorney/Law Firm
Parent Case
This application is a continuation of U.S. patent application Ser. No. 08/377,137 filed Jan. 20, 1995, now U.S. Pat. No. 5,789,426.
USPTO Field of Search
514/348   514/2  
Related Patents
Claims
Description
About| FAQs| Terms & Disclaimer| Link to Us| Contact Us