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Multiplexed analysis of clinical specimens apparatus and methods    
United States Patent5981180   
Link to this pagehttp://www.wikipatents.com/5981180.html
Inventor(s)Chandler; Van S. (Dallas, TX), Fulton; R. Jerrold (Cedar Hill, TX), Chandler; Mark B. (Austin, TX)
AbstractA method for the multiplexed diagnostic and genetic analysis of enzymes, DNA fragments, antibodies, and other biomolecules comprises the steps of constructing an appropriately labeled beadset, exposing the beadset to a clinical sample, and analyzing the combined sample/beadset by flow cytometry. Flow cytometric measurements are used to classify, in real-time, beads within an exposed beadset and textual explanations, based on the accumulated data obtained during real-time analysis, are generated for the user. The inventive technology enables the simultaneous, and automated, detection and interpretation of multiple biomolecules or DNA sequences in real-time while also reducing the cost of performing diagnostic and genetic assays.



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Inventor     Chandler; Van S. (Dallas, TX) , Fulton; R. Jerrold (Cedar Hill, TX) , Chandler; Mark B. (Austin, TX)
Owner/Assignee     Luminex Corporation (Austin, TX)
Patent assignment
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Publication Date     November 9, 1999
Application Number     08/540,814
PAIR File History     Application Data   Transaction History
Image File Wrapper   Patent Term   Fees
Litigation
Filing Date     October 11, 1995
US Classification     435/6 435/7.1 435/7.2 435/7.7 435/7.71 435/7.72 435/7.91 435/7.92 435/973 436/536 436/63
Int'l Classification    
Examiner     Housel; James C.
Assistant Examiner     Phan; Quang N
Attorney/Law Firm     Villacorta; Gilberto M. Pepper Hamilton LLP
Address
Parent Case     1. REFERENCES Commonly owned and patent application Ser. No. 08/542,401, entitled "Methods and Compositions for Flow Cytometric Determination of DNA Sequences by R. Jerrold Fulton, filed on Oct. 11, 1995, now U.S. Pat. No. 5,736,330 is hereby incorporated in its entirety by reference.
Priority Data    
USPTO Field of Search     435/973 435/7.1 435/7.2 435/7.7 435/7.72 435/7.91 435/7.92 435/6 436/534
Patent Tags     multiplexed analysis clinical specimens methods
   
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