Combinatorial libraries are disclosed which are represented by Formula I: ##STR1## wherein: ##STR2## is a solid support; T'--L-- is an identifier residue; and --L'--II' is a ligand/linker residue. These libraries contain dihydrobenzopyrans of the formula ##STR3## which interact (i.e., as agonists or antagonists) with .alpha. adrenergic receptors, dopamine receptors, .sigma.-opiate receptors, and K.sup.+ channels and are inhibitors of carbonic anhydrase isozymes. They are useful in the treatment of ocular diseases such as glaucoma.
CROSS REFERENCE TO RELATED APPLICATION
This is a CIP of U.S. Ser. No. 08/552,698, filed Nov. 3, 1995, now U.S. Pat. No. 5,821,130, which is a CIP of U.S. Ser. No. 08/436,120, filed May 8, 1995, abandoned, which is a CIP of U.S. Ser. No. 08/239,302, filed May 6, 1994, abandoned.
Combinatorial libraries are disclosed which are represented by Formula I: wherein: S is a solid support; T'--L-- is an identifier residue; and --L'--II' is a ligand/linker residue. These libraries contain dihydrobenzopyrans of the formula: ##STR1## which interact (i.e., as agonists or antagonists) with .alpha. adrenergic receptors, dopamine receptors, .delta.-opiate receptors, and K.sup.+ channels and are inhibitors of carbonic anhydrase isozymes. They are useful in the treatement of ocular diseases such as glaucoma.
