February 8, 2000

Compounds of formula (I) ##STR1## wherein n, V, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are as defined in the specification are matrix metalloproteinase inhibitors.

22

February 8, 2000

09/121,033

July 23, 1998

514/237.5   514/217.04 514/217.05 514/217.06 514/217.08 514/217.09 514/217.11 514/227.5 514/227.8 514/252.11 514/255.01 514/255.02 514/307 514/314 514/319 514/330 514/423 540/450 540/467 540/470 540/544 540/555 540/596 544/160 544/238 544/359 544/383 544/387 544/59 546/148 546/172 546/206 546/208 546/211 546/226 548/530 548/540

C07D   295/185   (20060101)   C07D   295/26   (20060101)   C07D   295/00   (20060101)  

This is a continuation-in-part application of International Application PCT/GB97/02891, with an international filing date of Oct. 20, 1997, which is based on Great Britain Application No. 9621814.4 filed Oct. 19, 1996.

Oct 19, 1996 [GB] 9621814

546/226   546/206   546/172   546/148   544/160   544/383   514/330   514/319   514/314   514/237.5   514/255   514/307