A pharmaceutical, orally applicable composition is described, whereby the solid composition contains at least one antacid active ingredient and/or at least one H.sub.2 -antagonist, at least one disintegrant, as well as at least one usual pharmaceutical additional ingredient. Furthermore said composition contains at least one ingredient that accelerates the decomposition of said composition in the mouth or in a liquid, whereby said ingredient is a water-soluble amino acid, a water-soluble amino acid derivative and/or a water-soluble amino acid salt.
