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Method of inhibiting hepatitis B virus
   
Document Number
US Patent 6037351
Issued Date
March 14, 2000
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Abstract
A method is disclosed for the treatment of hepatitis B virus (HBV) infections which comprises administering to the infected host an N-alkyl derivative of 1,5-dideoxy-1,5-imino-D-glucitol in which the alkyl group contains from 3 to 6 carbon atoms.
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Number of Claims:
3
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Owner
G. D. Searle & Co. (Chicago, IL)
Published
March 14, 2000
Application Number
08/676,153
Filed
July 11, 1996
US Classification
514/315  
Int'l Classification
A61K   31/445   (20060101)  
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Parent Case
CROSS-REFERENCE TO RELATED APPLICATION This is a 371 OF PCT/US94/14548 filed Dec. 23, 1994 which is a continuation-in-part of application Ser. No. 08/181,519, filed Jan. 13, 1994 now abandoned.
USPTO Field of Search
514/315  
Related Patents
6545021 - Use of substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds for treating hepatitis virus infections - Owned by G.D. Searle & Co. (Skokie, IL)

N-Substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds of Formula I are effective in treatment of hepatitis infections, including hepatitis B and hepatitis C. In treating hepatitis infections, the compounds of Formula I may be used alone, or in combination with another antiviral agent selected from among nucleosides, nucleotides, immunomodulators, immunostimulats or various combinations of such other agents.

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