An inhaler (1) for dispensing accurate and reproducible doses of powder. The inhaler includes an expulsion channel (2) opening out in an outlet orifice (3), and is characterized by a combination of or: a pre-dosing device (100) having the powder in individual reservoirs (101), each reservoir (101) containing one dose of powder, and; a transfer device (200) for transferring a dose of powder in full into the expulsion channel (2) on each actuation of the inhaler. The inhaler also includes an air flow source (300) having a pump (301) triggerable by the user the air flow source (300) sending a flow of air into the expulsion channel (2) towards the outlet orifice (3) to expel the dose of powder.
A system and method is described which utilizes a dual function reader device, which may be a hand-held inventory control device, which first performs an optical read of an optical bar code on a carrier unit, then based on the identification or other information obtained from the optical read a RF read is made of a RF tag attached to, or within, the carrier unit. An indicator light on the carrier unit illuminates when the optical read is completed, which allows an operator to visually verify that the optical read has transpired for the desired carrier unit. The RF tag provides data regarding the inventory of the goods stored within, or on, the carrier unit, the temperature of the goods, the shelf-life of the goods, the source and/or destination of the carrier unit and/or the goods, or other information. Data can also be written to the RF tag by the reader.
A disperser for dry powders which can be used with different dose systems, dose weights ranging from 2 to 25 mg and different types of powder formulation. In one embodiment, the disperser acts both as a de-agglomeration (disintegration; aerosolization) means and as an air classifier for especially adhesive mixtures. Only fine drug particles are emitted whereas the larger agglomerates and carrier crystals are retained by the disperser. Another embodiment enables time controlled release of carrier crystals in these mixtures. Yet another embodiment has optimized performance with spherical pellets, containing no carrier crystals. Other possible embodiments of the invention make it possible to control the total inhaler resistance and the powder deposition in the upper respiratory tract by means of the addition of a so-called sheath flow of clean air. Modifications also enable carrier retainment in the mouthpiece and elimination of the tangential flow component of the discharge cloud.