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Document Number
US Patent 6335193
Issued Date
January 1, 2002
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Inventors
Nair; Padmanabhan P (Ellicott City, MD)
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Abstract
A method for isolating viable, biologically substantially pure exfoliated fecal colonocytes at normal ambient temperature is described. Immunocoprocytes and inflammatory cells indicative of certain gastrointestinal conditions and a noninvasive method for detecting colorectal cancer are set forth. Composition of transport and suspension media for isolation of colonocytes are detailed.
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Number of Claims:
3
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Published
January 1, 2002
Application Number
09/292,358
Filed
April 15, 1999
US Classification
435/325  
Int'l Classification
C12N   5/06   (20060101)   C07K   16/40   (20060101)   C07K   16/00   (20060101)   G01N   33/574   (20060101)   G01N   33/68   (20060101)  
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USPTO Field of Search
435/325   435/378   435/363   435/366   435/371  
Related Patents
6821784 - Method of diagnosing colorectal adenomas and cancer using proton magnetic resonance spectroscopy - Owned by The University of Manitoba (Winnipeg,CA) National Research Council of Canada (Ottawa,CA) Board of Regents, University of Texas System (Austin, TX)

Two dimensional COSY magnetic resonance spectroscopy of human stool can be used in a non-invasive method of detecting the presence of colorectal cancer. The spectrum of a patient's stool is compared with that of stool from non-cancerous subjects, observed differences in spectra being indicative of cancer.

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Description
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